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Causal Physics-Informed Neural Networks Training System For Physical Simulation
A computer-based training system improves physics-informed neural networks (PINNs) training by weighted residual loss terms to account for physical causality. Problem: Conventional PINNs can struggle with dynamical systems that show multi-scale, chaotic, or turbulent behavior. Existing formulations may fail to respect the spatio-temporal causal structure...
Published: 7/28/2026   |   Updated: 7/28/2026   |   Inventor(s): Paris Perdikaris, Sifan Wang
Keywords(s): Artificial Intelligence (AI) & Machine Learning, Software
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Imaging
Image-Based Soft-Sensor Approach to Automate Microfluidic Control
Leveraging open-source AI platforms, this technology enables automated image-based detection, prediction, and control of microfluidic single bubble/droplet formation. Problem: Given the incorporation of microfluidic bubble/droplet generation in many applications of science and medicine, improving their high-quality throughout with minimal human intervention...
Published: 6/30/2026   |   Updated: 6/15/2026   |   Inventor(s): Daeyeon Lee, Owen Land, Warren Seider
Keywords(s): Artificial Intelligence (AI) & Machine Learning, Imaging Agents, Microfluidics, Soft Materials, Software
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Diagnostics, Technology Classifications > Imaging, Technology Classifications > Research Tools & Reagents, Technology Classifications > Robotics, Technology Classifications > Medical Devices, Technology Classifications > Hardware & Components
A Robust Training Platform for Real-World Analog AI Hardware
Bias-tolerant training method for analog AI hardware that improves learning stability without digital correction. Problem: Analog computing could enable faster, lower-power AI systems, but real devices are difficult to train reliably because physical hardware is inherently imperfect. Small biases in sensing, signal application, or component behavior...
Published: 7/24/2026   |   Updated: 5/19/2026   |   Inventor(s): Andrea Liu, Samuel Dillavou, Douglas Durian, Marcelo Guzman
Keywords(s): Artificial Intelligence (AI) & Machine Learning, Autonomous Vehicles, Internet of Things
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Hardware & Components, Technology Classifications > Robotics
Faster Distributed Systems Using Quasi-Synchrony
A way to organize distributed systems for data centers that require fewer resources and increase efficiency and predictability. Problem: Many distributed systems today are built on the assumption that the system is asynchronous - that packets can be lost or delayed arbitrarily and that clocks are at most weakly synchronized. This assumption results...
Published: 5/7/2026   |   Updated: 5/7/2026   |   Inventor(s): Andreas Haeberlen, Robert Gifford, Linh Thi Xuan Phan, Qingjie Lu, Karan Newatia
Keywords(s): Data Science, Software
Category(s): Technology Classifications > Computer Information Systems
Reflective Polymer Coating For Microscale Electronic Communication
A polymer coating which allows a device’s electrical activity to be optically transmitted based on its transparency. Problem: Existing wireless microscale communication platforms, such as radio-frequency antennas and micro-LEDs, are limited in their large footprint requirements relative to the chip size, have challenging integration pathways...
Published: 3/16/2026   |   Updated: 3/16/2026   |   Inventor(s): Marc Miskin, Matthew Campbell
Keywords(s): Electronic Materials, Nanotechnology, Platform Technology
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Hardware & Components, Technology Classifications > Materials
Tiny “Light-Twisting” Lasers For Faster, More Secure Encryption Keys
Quantum on-chip device that powers future ultra-secure, high-speed digital communication by encoding more information into single particles of light. Problem: Quantum key distribution (QKD) is a new way to create secure communication systems; however, it is limited to sending only a small amount of information at a time. Most current systems use qubits,...
Published: 7/24/2026   |   Updated: 2/8/2026   |   Inventor(s): Liang Feng, Yichi Zhang
Keywords(s): Electronic Materials
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Hardware & Components
Instant, Calibration-Free Blood-Flow Measurement With A Single Optical Snapshot
A single-frame, multi-exposure time optical method enabling accurate extraction of absolute speckle decorrelation time and optimized for recovery of absolute deep-tissue blood flow. Problem: Accurately recovering absolute speckle decorrelation time without the use of calibration or complex instrumentation is challenging. For the use case of monitoring...
Published: 7/24/2026   |   Updated: 1/8/2026   |   Inventor(s): Arjun Yodh, Wesley Baker, Joseph Majeski, Rodrigo Menezes Forti
Keywords(s): Bioengineering, Cardiovascular, Electronic Materials, Gastroenterology, Internet of Things, Nephrology and Urology, Neurology, Oncology, Ophthalmology, Optics & Photonics , Platform Technology, Surgery
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Diagnostics, Technology Classifications > Digital Health, Technology Classifications > Hardware & Components, Technology Classifications > Imaging, Technology Classifications > Research Tools & Reagents, Technology Classifications > Medical Devices, Technology Classifications > Testing & Measurement
Commercially Scalable Quantum Internet Architecture
A hybrid photonic system that enables quantum networking to scale across existing fiber infrastructure. Problem: Developing a commercially scalable quantum internet—one that can substantially reduce deployment costs by using existing fiber networks—is challenged by the fact that current quantum systems remain isolated laboratory platforms...
Published: 1/13/2026   |   Updated: 12/15/2025   |   Inventor(s): Liang Feng, Yichi Zhang, Robert Broberg, Jonathan Smith
Keywords(s): Electronic Materials, Optical/Photonic Architecture, Optics & Photonics 
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Hardware & Components, Technology Classifications > Materials
Electronic-Photonic Quadrature Delay-Locked Oscillator (DLO) For Efficient High-Speed Clock Generation And Distribution
A Quadrature Delay-Locked Oscillator that caters to increasing multi-GHz and multi-phase clock demands in systems such as time-interleaved architectures. Problem: The unrelenting growth of artificial intelligence (AI) requires advancements in high-performance hardware capable of delivering high-speed clock generation and distribution. These improvements...
Published: 10/29/2025   |   Updated: 10/29/2025   |   Inventor(s): Firooz Aflatouni, Henry Love
Keywords(s): Artificial Intelligence (AI) & Machine Learning, Electronic Materials, Optics & Photonics 
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Hardware & Components
SMOOTHLLM: Defending Large Language Models Against Jailbreaking Attacks
An algorithm designed to defend Large Language Models (LLMs) against jailbreaking attacks that significantly reduces attack success rates. Problem: Despite efforts to align LLM outputs with ethical standards, the models exhibit persistent weaknesses against adversarial attacks that bypass alignment mechanisms and safety guardrails, commonly known as...
Published: 7/10/2026   |   Updated: 1/28/2025   |   Inventor(s): George Pappas, Alexander Beck Robey, Seyed Hamed Hassani, Eric Wong
Keywords(s): Artificial Intelligence (AI) & Machine Learning, Software
Category(s): Technology Classifications > Business Ideas, Technology Classifications > Computer Information Systems
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