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Researchers at Stanford have developed a novel method for the barcoding of DNA. Over the past decade, single-cell sequencing has become widely used in biology and medicine. To analyze many cells at once, each cell must be labeled with a unique DNA barcode so its molecules can be identified after sequencing. This is usually done by capturing cells on...

Published: 4/15/2026 | Updated: 4/15/2026 | Inventor(s): Aaron Streets, Boden Eakins, Rodrigo Chaves

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Category(s): Technology Classifications > Biology

AUTOANTIBODIES FOR AUTOIMMUNE NEUROLOGICAL DISEASE DIAGNOSIS

Researchers at UCSF have developed a novel diagnostic for autoimmune neurological diseases. Autoimmune encephalitis and ataxia are serious neurological conditions that can be life-threatening if they are not diagnosed early. Diagnosis is challenging because symptoms vary widely, imaging and lab tests are often non-specific, and these diseases can...

Published: 4/15/2026 | Updated: 4/15/2026 | Inventor(s): Joseph DeRisi, Michael Wilson, Caleigh Mandel-Brehm, Samuel Pleasure

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Category(s): Technology Classifications > Biology

PROTEIN ONLY TOPICAL VACCINES AND METHODS OF USE

Researchers at Stanford have developed a novel vaccine strategy that would remove the need to use needles in vaccine administration. Vaccination is a highly effective and affordable way to prevent disease, saving an estimated 4.4 million lives each year. However, most vaccines require injection by trained healthcare workers, which can discourage people...

Published: 4/15/2026 | Updated: 4/15/2026 | Inventor(s): Michael Fischbach, Djenet Bousbaine

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Category(s): Technology Classifications > Biology

HIGH THROUGHPUT PRODUCTION OF PROTEIN VARIANTS

Researchers at Stanford have developed a novel high throughput system for the addition of amino acids into specific sites on proteins of interest. Classical biochemical assays yield rigorous kinetic and thermodynamic measurements but are slow, expensive, and inherently low-throughput, limiting their use in large-scale protein variant studies. Microfluidic...

Published: 4/15/2026 | Updated: 4/15/2026 | Inventor(s): Patrick Almhjell, Micah Olivas, Polly Fordyce

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Category(s): Technology Classifications > Biology

POTENT INHIBITORS OF THE PLASMODIUM PROTEASOME AND THEIR SYNTHESIS VIA A NOVEL ROUTE

POTENT INHIBITORS OF THE PLASMODIUM PROTEASOME AND THEIR SYNTHESIS VIA A NOVEL ROUTE Researchers at UCSF have developed a novel treatment for the causative pathogens for both malaria and tuberculosis respectively. Tuberculosis and malaria are caused by different infectious organisms, but both remain major global infectious diease health threats....

Published: 4/15/2026 | Updated: 4/15/2026 | Inventor(s):

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Category(s): Technology Classifications > Biology

Universal Chromatin Regulators as Transcriptional Modifiers Across Eukaryotes

CHROMATIN REGULATORS AS TRANSCRIPTIONAL MODIFIERS ACROSS EUKARYOTES Researchers at Berkeley and LBNL have developed a novel method for modifying gene transcription. In eukaryotic cells, DNA is packaged into chromatin, a dynamic structure that can shift between more open (euchromatin) and condensed (heterochromatin) states to regulate processes like...

Published: 4/15/2026 | Updated: 4/15/2026 | Inventor(s):

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Category(s): Technology Classifications > Biology

Diagnostic & prognostic immune markers for critical infections

DIAGNOSTIC AND PROGNOSTIC IMMUNE MARKERS FOR CRITICAL INFECTIONS Researchers at UCSF have discovered novel biomarkers for respiratory infections. Respiratory infections, like pneumonia, bronchitis, and viral illnesses, are a major global health problem, ranging from mild colds to serious conditions that require hospitalization. Infections in the...

Published: 4/15/2026 | Updated: 4/15/2026 | Inventor(s):

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Category(s): Technology Classifications > Biology

SYRINGOLINS AS INHIBITORS OF THE MYCOBATERIAL PROTEASOME

SYRINGOLINS AS INHIBITORS OF THE MYCOBACTERIAL PROTEASOME Researchers at UCSF have discovered a novel prospective compound for the treatment of tuberculosis. Tuberculosis is caused by the bacterium Mycobacterium tuberculosis (Mtb) and is one of the deadliest infectious diseases worldwide. As more strains become resistant to existing drugs, it’s...

Published: 4/15/2026 | Updated: 4/15/2026 | Inventor(s):

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Category(s): Technology Classifications > Biology

PHOTOCLEAVABLE INTERFERING GUIDE RNAS

PHOTOCLEAVABLE INTERFERING GUIDE RNAS AND USE THEREOF Researchers at Berkeley have developed a novel method of light sensitive control of Cas proteins. CRISPR-based diagnostic tools can detect DNA or RNA with high sensitivity and specificity. In these systems, enzymes like Cas13a use a guide RNA to find a matching target sequence, which activates...

Published: 4/15/2026 | Updated: 4/15/2026 | Inventor(s): Daniel Fletcher, Deepak Krishnamurthy, Carlos Pitti

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Category(s): Technology Classifications > Biology

PREDICTING 3D GENOME ARCHITECTURE FROM SINGLE-MOLECULE SEQUENCING DATA

Researchers at Stanford have developed FiberFold, a computational tool enabling the rapid analysis of 3D chromatin architecture in conjunction with chromatin accessibility, CTCF binding, CpG methylation, and underlying genetic architecture. To gain a comprehensive understanding of the genomic regulatory landscape, it is essential to investigate various...

Published: 10/23/2025 | Updated: 10/23/2025 | Inventor(s): Nicolas Altemose, Danilo Dubocanin

Keywords(s): Chromatin, Genomic, Machine Learning, Sequencing

Category(s): Technology Classifications > Biology

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