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Search Results - takuya+maeda
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Star, Branched, and Graft Polymers in Binders for Inkjet Additive Manufacturing for Personalized Dosage Tablets
THE CHALLENGE A major problem posed by the pharmaceutical industry is giving effective dosages while not giving excessive amounts of a particular drug. An estimated 80% of side effects in humans and animals are a direct result of inaccurate dosing because varying weights in patients. Additive manufacturing has emerged as a very promising method to...
Published: 1/31/2024
|
Inventor(s):
Emily Wilts
,
Timothy Long
,
Christopher Williams
,
Da Ma
Keywords(s):
Category(s):
Technology Classifications > Additive Manufacturing
,
Technology Classifications > Biomedical
,
Technology Classifications > Chemicals/Materials
,
Technology Classifications > Pharmacology and Therapeutics
High-Throughput Generation of Induced Pluripotent Stem Cells Carrying Antigen-Specific T Cell Receptors from Tumor Infiltrated Lymphocytes
Abstract: One form of adoptive T cell therapy (ACT) consists of harvesting tumor infiltrating lymphocytes (TIL), screening and isolating TIL which display tumor antigen-specific T-cell receptors (TCR), expanding the isolated T cells in vitro, and reinfusing them into the patient for treatment. While highly active in the treatment of certain cancers...
Published: 4/8/2024
|
Inventor(s):
Raul Sakoda
,
S M Rafiqul Islam
,
Naritaka Tamaoki
,
Takuya Maeda
,
Nicholas Restifo
Keywords(s):
act
,
adoptive cell therapy
,
ANTIGEN-SPECIFIC
,
Cancer Targets
,
Immunotherapy
,
Induced Pluripotent Stem Cells
,
iPSC
,
Restifo
,
Rosenberg
,
T Cell Receptors
,
TCR
,
TIL
,
Tumor Infiltrated Lymphocytes
Category(s):
TherapeuticArea > Oncology
,
TherapeuticArea > Immunology
,
Application > Therapeutics
,
Collaboration Sought > Licensing