Search Results - stephan+bour

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Codon-optimization of HIV-1 Viral Infectivity Factor (VIF) Gene
Expression of the HIV-1 Vif protein in the absence of other viral factors such a Tat and Rev is extremely inefficient due to the presence of inhibitory sequences on its mRNA. This invention uses codon optimization to remove such inhibitory sequences without altering the amino acid sequence of the protein. The modified vif gene in the resulting pcDNA...
Published: 10/28/2024   |   Inventor(s): Klaus Strebel, Stephan Bour, Kim-Lien Nguyen
Keywords(s): AAXXXX, AXXXXX, DA4AXX, DAXXXX, DDXXXX, DXXXXX, PLASMID, RM, VLXXXX, WIXXXX
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Research Materials, Application > Diagnostics