Search Results - stacey+van+pelt

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Engineered Immune Cells for Targeted Tumor Infiltration and Enhanced CAR-T cell Therapy
CAR-T cell therapy has emerged as a promising cancer treatment, leveraging patient’s own T cells that are genetically modifying to express a Chimeric Antigen Receptor (CAR). These receptors enable T cells to recognize and attack antigens on the surface of cancerous cells more effectively. While highly effective against certain cancers, solid...
Published: 2/26/2025   |   Inventor(s): Rohan Fernandes, Bilal Omer, Stacey Van Pelt
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics > Proteins and Peptides
Immunotherapies Targeting SSX2 Peptide Displayed by MHC on Tumors
­Chimeric Antigen Receptor (CAR) T cells are making headlines with their recent FDA approvals and ability to eradicate cancers. Most CAR T therapies target tumor cells via a tumor associated antigen (TAA). Unfortunately, TAAs are also expressed on non-cancerous tissues, leading to significant risk for patients. SSX2 protein expression is restricted...
Published: 2/18/2025   |   Inventor(s): Eric Yvon, Catherine Bollard, Stacey Van Pelt, Scott Raskin, Gerhard Held, Christine Sturm, Michael Pfreundschuh
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Proteins and Peptides