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Search Results - eric+yvon
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Medium for freezing and thawing T cells or NK cells for therapies or diagnostics
Immune cells display a range of phenotypes (eg. regulatory, memory, or activated) that are regulated by and regulate the assortment of proteins expressed on their surface. Unfortunately, freezing and thawing of immune cells causes loss of important surface proteins. In the case of cell therapies (like T cell or NK cell), loss of surface proteins...
Published: 7/30/2024
|
Inventor(s):
Eric Yvon
,
Joshua Kellner
Keywords(s):
Category(s):
Technology Classifications > Research Tools > Buffers and Media
Immunotherapies Targeting SSX2 Peptide Displayed by MHC on Tumors
Chimeric Antigen Receptor (CAR) T cells are making headlines with their recent FDA approvals and ability to eradicate cancers. Most CAR T therapies target tumor cells via a tumor associated antigen (TAA). Unfortunately, TAAs are also expressed on non-cancerous tissues, leading to significant risk for patients. SSX2 protein expression is restricted...
Published: 7/30/2024
|
Inventor(s):
Eric Yvon
,
Catherine Bollard
,
Stacey Van Pelt
,
Scott Raskin
,
Gerhard Held
,
Christine Sturm
,
Michael Pfreundschuh
Keywords(s):
Category(s):
Technology Classifications > Therapeutics > Proteins and Peptides