Search Results - shashank+shukla

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Fluorogenic bioconjugation of cyclopropanol-containing fluorophores for biological applications
Reference #: 1742 The University of South Carolina is offering licensing opportunities for Fluorogenic bioconjugation of cyclopropanol-containing fluorophores for biological applications. Background: Fluorophores have been used in various applications of cellular microbiology, most notably with the reporting functions associated with various biological...
Published: 1/13/2025   |   Inventor(s): Qian Wang, Shan Hu
Keywords(s):  
Category(s): Chemistry and Biochemistry
Cyclopropanol as a bioorthogonal warhead for electrochemically controlled bioconjugation applications
Reference #: 1685 The University of South Carolina is offering licensing opportunities for Cyclopropanol as a bioorthogonal warhead for electrochemically controlled bioconjugation applications. Background: Bioconjugation techniques play an important role in modern chemical biology and biomedical sciences, such as protein drug stabilization, target...
Published: 11/11/2024   |   Inventor(s): Qian Wang, Shan Hu
Keywords(s):  
Category(s): Biomedical and Life Sciences, Health Sciences
Novel Chromogenic Beta-Lactamase Substrate for Diagnostic Biomaterials
Overview Chromogenic beta-lactamase substrates are used to diagnose bacterial infections. Yet those currently available lose their diagnostic color-change capability when chemically modified. We have synthesized a novel chromogenic beta-lactam molecule (“ANT”) that retains its color-change response when modified for conjugation to a range...
Published: 3/5/2025   |   Inventor(s): Anita Shukla, Dahlia Alkekhia, Shashank Shukla, Hannah Safford
Keywords(s):  
Category(s): Diagnostics, Drug Delivery
Systems and Methods of Using Phase Change Material in Power Plants
PAGE TITLEOverviewPAGE SUMMARY Cooling systems and methods for cooling in a power plant using a phase change material. In one embodiment, a phase change material container includes at least one phase change material which may be in the form of a slurry; and at least one conduit for transporting the fluid through the phase change material when located...
Published: 2/19/2025   |   Inventor(s): Matthew Mccarthy, Ying Sun, Young Cho, Baolan (jessica) Shi, Han Hu, Philipp Boettcher, Qinghua (tim) Xie
Keywords(s):  
Category(s): Energy, Advanced Materials & Chemicals, Construction & Civil Engineering
Tunable Antimicrobial-Loaded Gellan Hydrogels for Burn Wound Dressings
Overview The standard practice of treating burn wounds preventatively with broad-spectrum antibiotics contributes to the growing problem of antibiotic resistance. Exposure to systemic antibiotics also leads to toxicity in unaffected tissues. Using FDA-approved methods, we have developed a gellan hydrogel delivery system with tunable mechanical and...
Published: 3/5/2025   |   Inventor(s): Anita Shukla, Shashank Shukla
Keywords(s):  
Category(s): Drug Delivery