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Search Results - shar-yin+huang
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Synergistic Use of Exo VII Inhibitors And Quinolone Antibiotics For Treating Bacterial Infection
Abstract: Topoisomerase poisons, such as quinolone antibiotics, are widely used as anticancer drugs and antibiotics. Quinolone antibiotics act by trapping prokaryotic type IIA topoisomerases (DNA gyrase and TOPO IV), resulting in irreversible topoisomerase cleavage complexes. However, current U.S. Food and Drug Administration (FDA) guidance reserves...
Published: 4/22/2025
|
Inventor(s):
Yves Pommier
,
Shar-yin Huang
,
Brianna Mitchell
Keywords(s):
Antibacterial
,
Antibiotic Adjuvants
,
Antibiotic Resistance
,
DNA gyrase
,
Exonuclease VII
,
ExoVII
,
Infection
,
Pommier
,
Quinolone
,
TOPO IV
,
Topoisomerase Poisons
Category(s):
Collaboration Sought > Licensing
,
Collaboration Sought > Collaboration
,
TherapeuticArea > Infectious Disease
,
Application > Therapeutics
Processing Technique for Ceramic- based Energy Conversion and Storage Devices
Due to rising carbon emissions, extreme weather events and other environmental threats, the demand for alternative energy sources is greater than ever. Therefore, businesses and communities are asking for three things: more affordable electricity, more resilient power, and cleaner energy. Fuel cells, electrolysis cells, membrane reactors, and solid-state...
Published: 10/8/2024
|
Inventor(s):
Hai Xiao
,
Jianhua Tong
,
Fei Peng
,
Kyle Brinkman
,
Jincheng Lei
,
Yuzhe Hong
,
Hua Huang
,
Shenglong Mu
,
Rajendra Bordia
Keywords(s):
Category(s):
Manufacturing
Automated Pain Detection in Pediatric Care
uot;Times New Roman",serif; font-size:12pt">Unmet Need: Continuous pain assessment in infants Continuing advances in intensive care have made it possible for premature infants to survive outside the uterus in Neonatal Intensive Care Unit (NICU) even at very early stages of development. Infants in the NICU may receive an estimated 10-14 painful...
Published: 10/8/2024
|
Inventor(s):
Subhanshu Gupta
,
Huan Hu
,
Martin Schiavenato
Keywords(s):
Category(s):
Technologies > Health & Well-being > Health-IT
,
Technologies > Health & Well-being > Medical Devices
,
Technologies > Energy & Environment > Computer Hardware/Software
,
Technologies > Energy & Environment > Electrical/Electronics