Search Results - ryan+macarthur

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Multi-parametric Acoustic, Optical and Mechanical Imaging of Cervical Tissue Insufficiencies to Predict Preterm Birth
An enhanced image-guidance system that integrates ultrasound and photoacoustic into existing ablation systems to provide an enhanced image-guidance system for identification of cervical tissue changes during pregnancy and postpartum. Technology Summary Preterm delivery is a main cause of perinatal morbidity and mortality worldwide, which is associated...
Published: 9/15/2025   |   Inventor(s): Mohammad Mehrmohammadi, Sonia Hassan, Edgar Hernandez-Andrade, Yan Yan, Maryam Basij
Keywords(s): Driving Lifelong Health
Category(s): Life Science, Medical Devices, Imaging, Acoustics, Women's Health
Potent and Selective Cyclic Peptide Inhibitors of Phosphoglycerate Mutase as Anti-Infective Agents
Summary – The invention includes compounds and compositions for inhibiting phosphoglycerate mutase (PGM) activity. In some examples, the compounds selectively inhibit cofactor-independent PGM (iPGM). In particular embodiments, the compounds include one or more cyclic peptides. Brief Background – Co-factor independent phosphoglycerate mutase (iPGM)...
Published: 10/28/2024   |   Inventor(s): Patricia Dranchak, Ryan Macarthur, James Inglese
Keywords(s): Agents, Anti-infective, Cyclic, DB2XXX, DB3XXX, Inhibitors, Mutase, Peptide, Phosphoglycerate, POTENT, SELECTIVE, VJXXXX, VQXXXX
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Therapeutics