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Search Results - rongfu+wang
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PSM Peptides as Vaccine Targets Against Methicillin-Resistant Staphylococcus aureus
Available for licensing and commercial development are compositions and methods for the treatment and inhibition of Methicillin-resistant Staphylococcus aureus (MRSA), a dangerous human pathogen. The invention concerns immunogenic peptides that can be used to induce protective immunity against MRSA, including phenol-soluble modulin (PSM) peptides. In...
Published: 10/28/2024
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Inventor(s):
Rong Wang
,
Michael Otto
Keywords(s):
Against
,
ANTIBIOTIC
,
AUREUS
,
CA-MRSA
,
DB3XXX
,
DBXXXX
,
DC4XXX
,
DCXXXX
,
DXXXXX
,
fasciitis
,
Gene
,
GenePeptides
,
Immunity
,
Immunogenic
,
Methicillin-resistant
,
MRSA
,
necrotizing
,
necrotizing fasciitis
,
Peptides
,
PMS
,
PSM
,
Staphloccus
,
STAPHYLOCOCCAL
,
Staphylococcus
,
Targets
,
Vaccine
Category(s):
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
Application > Vaccines
,
Application > Therapeutics
,
TherapeuticArea > Infectious Disease
Beclin 2-Functionalized Therapies for Treatment of Neurodegenerative Disease and Cancer
This invention identified that Beclin 2 functions as a negative regulator of the ERK1/2 signaling, NF-κB signaling, and inflammasome activation. Furthermore, these studies demonstrated that Beclin 2 targets key signalling kinases for degradation through an ATG9A-dependent autophagic pathway. These new findings have uncovered an important role...
Published: 9/13/2024
|
Inventor(s):
Rongfu Wang
,
Helen (Yicheng) Wang
,
Motao Zhu
Keywords(s):
Category(s):
Clinical Area > Cancer
,
Clinical Area > Neurology
,
Research Area > Cancer
,
Research Area > Immunobiology and Inflammation
,
Research Area > Neurology and Neurosurgery
,
Technology Classifications > Therapeutic > Biologics
,
Technology Classifications > Therapeutic > Small Molecules
,
Technology Classifications > Therapeutic > Immunotherapy