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Search Results - ritu+aneja
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Brominated Noscapine as a Potent Anti-Inflammatory
Key Benefits Noscapine has been used safely in humans for over 30 years. Noscapine analogs can inhibit inflammation in in vitro models. Technical Summary The innate immune system plays a crucial role in host defense and homeostasis. Innate immune responses are induced when pattern recognition receptors such as Toll-like receptors (TLR) sense...
Published: 11/20/2024
|
Inventor(s):
Susu Zughaier
,
Ritu Aneja
,
David Stephens
Keywords(s):
Immunology/Inflammation
,
Small Molecule
Category(s):
TechPub Algolia > Therapeutics
Targetin: New Targeted Non-Toxic Anti-Cancer Drug
Application Compositions and methods for treating cancer and inflammatory disease using noscapine and noscapine analogues conjugated to targeting molecules. Key Benefits Noscapine is a plant-derived alkaloid with a long-history of human use as an anti-cough agent. Noscapine is currently in phase I clinical trials for the treatment...
Published: 12/4/2024
|
Inventor(s):
Harish Joshi
,
Suryan Vangapandu
,
Ritu Aneja
Keywords(s):
Oncology
,
Small Molecule
Category(s):
TechPub Algolia > Therapeutics
Synthesizing Noscapine Analogues for Drug Resistance
Application Synthesis of noscapine analogs and their use as cancer treatments, including drug resistant cancers. Key BenefitsEfficient, high yielding synthesis of noscapine derivatives. Selective for cancer cells over normal human cells.Technical Summary The effectiveness of microtubule-targeting drugs as treatments for cancer has been validated through...
Published: 12/4/2024
|
Inventor(s):
Harish Joshi
,
Ritu Aneja
Keywords(s):
Imaging Agents
,
Oncology
,
Small Molecule
Category(s):
TechPub Algolia > Therapeutics