Search Results - raymond+birge

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Inhibitors of Gas6-Axl Signaling Pathway as First of Kind Cancer Therapeutics
Gas6 activates TAM receptor (Axl)inducing signaling cascade to promote tumor cell proliferation, migration and survival. Invention Summary: TAM receptors (Tyro-3, Axl, and Mer) belong to a family of receptor tyrosine kinases (RTKs) that play essential roles in homeostasis and inflammation. Axl is overexpressed in many human cancers and is clinically...
Published: 12/8/2025   |   Inventor(s): William Welsh, Raymond Birge, Vladyslav Kholodovych, Youyi Peng, Stanley Kimani, Thomas Comollo, Kamalendra Singh
Keywords(s): Anti-cancer, Brain Cancer, Breast Cancer, Cancer biomarkers
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
Novel Phosphatidylserine-Targeting Immunobiologicals for Cancer and Viral Treatment
PS-targeting biological inhibits tumor growth and virus infection Invention Summary: Phosphatidylserine (PS) is a phospholipid that is restricted to the inner plasma membrane in healthy cells but is externalized in apoptotic or stressed cells abundantly present in tumor microenvironment or in sites of virus infection. PS is also present on the...
Published: 9/4/2025   |   Inventor(s): Sergei Kotenko, Viralkumar Davra, Raymond Birge
Keywords(s): Anti-cancer, Antiviral
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics