Search Results - pyrophosphate

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Pyrophosphate Analog HIV-1 Reverse Transcriptase Inhibitors
The invention relates to compounds that inhibit HIV-1 DNA synthesis mediated by reverse transcriptase (RT). HIV-1 DNA synthesis by RT utilizes deoxynucleoside 5’-triphosphate (dNTP) as substrate and like many other enzymes, the reaction is reversible. Pyrophosphate analogs like imidodiphosphate strongly promote reverse reaction dNTP products containing...
Published: 10/28/2024   |   Inventor(s): William (Bill) Beard, David Shock, Samuel Wilson
Keywords(s): DB4AXX, HIV-1, INHIBITING, PYROPHOSPHATE, TRANSCRIPTASE, VLXXXX, YBXXXX
Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Infectious Disease
Stiff Gel Adhesives for Underwater Use
Project ID: D2014-08Background Underwater adhesion has several potential medical, household and industrial applications. Generally, underwater adhesives have been prepared using methods that rely on in situ polymerization, covalent crosslinking, or the use of highly specialized biological or biomimetic polymers. Despite current strategies, many challenges...
Published: 6/18/2024   |   Inventor(s): Yakov Lapitsky, Yan Huang
Keywords(s): Adhesive, Controlled Release, Gels, PAH, Poly(allylamine), PPi, Pyrophosphate, TPP, Tripolyphosphate, Underwater
Category(s): Polymers, Tools