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Search Results - david+shock
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Pyrophosphate Analog HIV-1 Reverse Transcriptase Inhibitors
The invention relates to compounds that inhibit HIV-1 DNA synthesis mediated by reverse transcriptase (RT). HIV-1 DNA synthesis by RT utilizes deoxynucleoside 5’-triphosphate (dNTP) as substrate and like many other enzymes, the reaction is reversible. Pyrophosphate analogs like imidodiphosphate strongly promote reverse reaction dNTP products containing...
Published: 10/28/2024
|
Inventor(s):
William (Bill) Beard
,
David Shock
,
Samuel Wilson
Keywords(s):
DB4AXX
,
HIV-1
,
INHIBITING
,
PYROPHOSPHATE
,
TRANSCRIPTASE
,
VLXXXX
,
YBXXXX
Category(s):
Collaboration Sought > Collaboration
,
Application > Therapeutics
,
TherapeuticArea > Infectious Disease