Search Results - pharmaceuticals+%26+therapeutics+%3e+pharma%3a+neurodegeneration

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Glutamate Modulators to Treat Neurological and Psychiatric Disorders
PAGE TITLE Overview PAGE SUMMARY Prof. Sandhya Kortagere of Drexel University has developed glutamate transport modulators for treating neurological disorders caused by glutamate dysregulation. These drugs increase clearance of the neurotransmitter glutamate by cells containing GLT-1, an important modulator of the glutamatergic system. Administration...
Published: 8/27/2024   |   Inventor(s): Sandhya Kortagere
Keywords(s):  
Category(s): Pharmaceuticals & Therapeutics, Pharmaceuticals & Therapeutics > Pharma: Neurology, Pharmaceuticals & Therapeutics > Pharma: Neurodegeneration
NOVEL GLUTAMATE TRANSPORTER ACTIVATORS AND METHODS USING SAME
PAGE TITLENeuroprotective agent for Parkinson’s DiseasePAGE SUMMARYParkinson’s Disease (PD) is a progressive neurological disorder whose prevalence increases with age and certain genetic predispositions. It is estimated that 7-10 million people are affected by Parkinson’s Disease worldwide, with 1 million in the United States. Currently,...
Published: 8/27/2024   |   Inventor(s): Sandhya Kortagere, Ole Mortensen, Andreia Mortensen, Joseph Salvino
Keywords(s):  
Category(s): Pharmaceuticals & Therapeutics, Pharmaceuticals & Therapeutics > Pharma: Neurodegeneration, Pharmaceuticals & Therapeutics > Pharma: Neurology
A new method to study and manipulate APP processing and amyloidogenesis
PAGE TITLE A new method to alter amyloid precursor protein processing and amyloidogenesis PAGE SUMMARY Altered Amyloid Precursor Protein (APP) processing and Aβ production have long been recognized as major factors in the cognitive decline associated with both Alzheimer’s Disease (AD) and HIV-Associated Neurocognitive Disorders (HAND)....
Published: 8/2/2024   |   Inventor(s): Olimpia Meucci, Renato Brandimarti
Keywords(s):  
Category(s): Research Tools & Materials, Pharmaceuticals & Therapeutics, Pharmaceuticals & Therapeutics > Pharma: Neurodegeneration
Novel compositions useful in treating brain-related diseases or disorders and methods using same
PAGE TITLEOverviewPAGE SUMMARY The present invention provides compounds useful for treating or preventing a brain-related disease or disorder. The present invention further provides a method of treating or preventing a brain-related disease or disorder in a patient, the method comprising administering to the patient a pharmaceutical composition comprising...
Published: 8/27/2024   |   Inventor(s): Sandhya Kortagere, Ole Mortensen, Andreia Mortensen, Joseph Salvino
Keywords(s):  
Category(s): Pharmaceuticals & Therapeutics, Pharmaceuticals & Therapeutics > Pharma: Neurodegeneration, Pharmaceuticals & Therapeutics > Pharma: Neurology