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Mirror Effect Plus Protocol (MEPP) 2.0: plate-forme de rééducation faciale

MEPP: A Revolutionary Web Platform for Facial Rehabilitation An innovation combining mirror therapy and augmented reality UNMET NEED Each year, approximately 2.4 million people suffer from Bell’s palsy, and another 2 million develop facial paralysis following a stroke. Between 20% and 30% of this affected population would require facial...

Published: 6/23/2025 | Inventor(s): Karine Marcotte, Akram Rahal, Sarah Martineau

Keywords(s): Innovation

Category(s): Secteurs > Sciences de la vie, Sectors > Life sciences, Applications > Soins et santé > Gestion de santé (Santé digitale), Applications > Soins et santé > Traitement, English Applications > Health and care > Healthcare management (digital healthcare), English Applications > Health and care > Treatment, Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être, Sustainable Development Goals > Goal 03: Good Health and Well-Being

CBLs as a biomarker of and target to treat systemic lupus erythematosus (SLE)

SLE DIAGNOSTIC TOOL CBL protein levels used as a molecular diagnostic marker to diagnose and assess severity of Systemic Lupus Erythematosus (SLE) Systemic Lupus Erythematosus patient (photo: NCRD) UNMET NEED Systemic Lupus Erythematosus (SLE) is an autoimmune disease, especially prevalent in women, and without curative treatment. In addition,...

Published: 6/13/2025 | Inventor(s): Xin Li, Zhe-Xiong Lian, Hua Gu

Keywords(s): Innovation

Category(s): Applications > Soins et santé > Diagnostic, English Applications > Health and care > Diagnostic-ENG, Secteurs > Sciences de la vie, Sectors > Life sciences, Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être, Sustainable Development Goals > Goal 03: Good Health and Well-Being

Detection of HIV-1 soluble gp120 in biological fluids

HIV gp120 monitoring in body fluids Personalized medicine tool for patient stratification and follow-up of fostemsavir (Rukobia) treatment based on the detection of HIV soluble gp120 in biological fluids HIV-CD4 binding mechanism Reference : Zuru DU, Sci African 6: e00177, 2019. UNMET NEED A significant number of people living with HIV...

Published: 6/19/2025 | Inventor(s): Jonathan Richard, Marzena Pazgier, Mehdi Benlarbi, Andrés Finzi

Keywords(s): Innovation

Category(s): Applications > Soins et santé > Diagnostic, English Applications > Health and care > Diagnostic-ENG, Secteurs > Sciences de la vie, Sectors > Life sciences, Sustainable Development Goals > Goal 03: Good Health and Well-Being, Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être

Angiographie Myocardique Ultrasonore Super Résolue (MULA)

High Resolution Angiography in Moving Organs Dynamic Myocardial Ultrasound Localization Angiography (MULA) Credit Shutterstock : 649269142 UNMET NEED In patients with known or suspected coronary heart disease, cardiac imaging tests are often the first step in diagnosis and treatment planning. However, they remain for the most part limited...

Published: 6/16/2025 | Inventor(s): Jonathan Porée, Philippe Cormier, Jean Provost

Keywords(s): Innovation, Startup

Category(s): Applications > Soins et santé > Diagnostic > Imagerie médicale (IRM, Ultrasons, tomographie, OCT…), Secteurs > Sciences et génie, English Applications > Health and care > Diagnostic-ENG > Medical imaging (MRI, ultrasound, tomography, OCT, etc.), Sustainable Development Goals > Goal 03: Good Health and Well-Being, Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être, Sectors > Science and Technologies

Novel Antisense Oligonucleotides Targeting RAPTOR Expression to Improve the Pathological Consequences of Genetic Mutations Causing mTORC1 Hyperactivity, including GATOR1 and TSC mutations.

NOVEL RNA INTERFERENCE AGENTS TARGETING mTORC1 ACTIVITY New hope for epilepsy and autism spectrum disorders (ASD) Shutterstock : 2203572829 UNMET NEED Epilepsy and Autism Spectrum Disosrder (ASD) are significant public health concerns, affecting over 65 million people worldwide for epilepsy and 1 in 100 children worldwide (1 in 36 children...

Published: 6/19/2025 | Inventor(s): Antoine Desmeules, Paul Dutchak

Keywords(s): Innovation

Category(s): Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être, Sustainable Development Goals > Goal 03: Good Health and Well-Being, Secteurs > Sciences de la vie, Sectors > Life sciences, Applications > Soins et santé > Traitement > Pharmaceutique > Neurologie, Applications > Soins et santé > Traitement > Pharmaceutique > Système nerveux central, English Applications > Health and care > Treatment > Pharmaceuticals > Neurology, English Applications > Health and care > Treatment > Pharmaceuticals > Central nervous system

Methods and composition for gene editing at the transferrin locus

Gene editing toolbox Cas-9-based proprietary tools for gene editing, better production and efficient CAR-T cells, and/or transfer of therapeutic proteins across the blood-brain barrier Shutterstock : 2166283693 UNMET NEED Pediatric metabolic diseases. There is currently no approved long-term therapy or cure for several diseases such as type...

Published: 6/19/2025 | Inventor(s): Jean-François Rivest, Yannick Doyon

Keywords(s): Innovation

Category(s): Secteurs > Sciences de la vie, Sectors > Life sciences, Sustainable Development Goals > Goal 03: Good Health and Well-Being, Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être, Applications > Soins et santé > Traitement > Biotechnologies, English Applications > Health and care > Treatment > Biotechnologies-T

Layer-by-layer modified lipid nanoparticles for enhanced gene and drug delivery and applications thereof

LbL MODIFIED LNPs - GENE & DRUG DELIVERY New layer-by-layer (LbL) assembled Lipid nanoparticles (LNPs) platform for high biomolecule loading, staged release, adequate protection of cargo and modulated targeting property. Shutterstock : 2166283693 UNMET NEED The development of nanocarriers capable of encapsulating, targeting, and delivering...

Published: 6/19/2025 | Inventor(s): Chun Yang, Xavier Banquy, Victor Passos Gibson, Houda Tahiri, Pierre Hardy

Keywords(s): Innovation

Poly (monoglycerol acrylate) - PMGA

POLY (MONOGLYCEROL ACRYLATE) New alternative to PEG in lipid nanoparticles (LNP) Shutterstock : 2203572829 UNMET NEED Poly (ethylene glycol) (PEG) is widely used in pharma to 1) prepare bioconjugates and 2) generate lipid nanoparticles (LNPs). In LNPs that contain nucleic acids, PEG-lipids facilitate the preparation of stable colloids, but...

Published: 6/19/2025 | Inventor(s): Sabrina Roussel, Philippe Grenier, Nicolas Bertrand

Keywords(s): Innovation

Category(s): Applications > Soins et santé > Traitement > Biotechnologies, English Applications > Health and care > Treatment > Biotechnologies-T, Secteurs > Sciences de la vie, Secteurs > Sciences et génie, Sectors > Life sciences, Sectors > Science and Technologies, Sustainable Development Goals > Goal 03: Good Health and Well-Being, Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être

Agonistic antibodies against SLAMF7 for improved immunotherapy against human cancer

Novel Multiple Myeloma Therapy trough SIRP-alpha and SLAMF7 blockade New and first-in-class anti-SLAMF7 monoclonal antibody (Z10) Credit Shutterstock : 1878567847 UNMET NEED Multiple myeloma is a hematological cancer characterized by a clonal expansion of plasma cells. There are approximatively 2500 new cases per year in Canada and 35000...

Published: 6/13/2025 | Inventor(s): Ming-Chao Zhong, Jin Qian, Zhenghai Tang, André Veillette

Keywords(s): Innovation

Category(s): Applications > Soins et santé > Traitement > Pharmaceutique > Oncologie, English Applications > Health and care > Treatment > Pharmaceuticals > Oncology, Secteurs > Sciences de la vie, Sectors > Life sciences, Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être, Sustainable Development Goals > Goal 03: Good Health and Well-Being

Quantification objective de la variation du niveau de douleur basée sur le coefficient de variation de l'enveloppe des signaux EEG

EEG for pain quantification Objective and accurate pain measurement Credit Emotiv UNMET NEED Pain is one of the most common symptoms, seen in many diseases, that brings patients to a physician. Also, chronic pain is now recognized as a disease in its own right by the WHO (ICD-11). As this could suggest, pain is measured as an outcome in many...

Published: 6/13/2025 | Inventor(s): Colince Segning Meli, Suzy Ngomo

Keywords(s): Innovation

Category(s): Applications > Soins et santé > Diagnostic > Imagerie médicale (IRM, Ultrasons, tomographie, OCT…), Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être, Sustainable Development Goals > Goal 03: Good Health and Well-Being, Secteurs > Sciences de la vie, Sectors > Life sciences, Applications > Soins et santé > Diagnostic > Dispositifs médicaux (diagnostic), English Applications > Health and care > Diagnostic-ENG > Medical devices, English Applications > Health and care > Diagnostic-ENG > Medical imaging (MRI, ultrasound, tomography, OCT, etc.)

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