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Search Results - n-methoxyoxoacetyl-glycine
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Prevention and Treatment of Herpes Virus Infection by Inhibition of the JMJD2 Family of Histone Demethylases
Investigators at the NIH have discovered a potential means for preventing or treating a herpes virus infection by inhibiting the activity of the host cell’s histone demethylases. When herpesviruses enter a cell, they are inactivated by cellular defense mechanisms that wrap the viral genome in repressive chromatin structures. In order for viral replication...
Published: 10/28/2024
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Inventor(s):
Yu Liang
,
Jodi Vogel
,
Jesse Arbuckle
,
Thomas Kristie
Keywords(s):
Analogs
,
Chicken pox
,
CYTOMEGALOVIRUS
,
DB4XXX
,
DBXXXX
,
DEPLETION
,
Dimethyloxalylglycine
,
DMOG
,
DXXXXX
,
ENZYMES
,
Ester
,
FAMILY
,
HERPES
,
INFECTIONS
,
Inhibitors
,
JMJD
,
Kaposi Sarcoma
,
Kaposi's sarcoma; Kaposi sarcoma
,
Latency
,
Methyl
,
N-methoxyoxoacetyl-glycine
,
Patent Category - Chemistry
,
Prevent
,
Reactivation
,
simplex
,
Varicella Zoster
,
virus
Category(s):
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
Application > Therapeutics
,
TherapeuticArea > Infectious Disease