Search Results - microfluidics

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New Optical Tweezers for Rapid Control of Nanoscale Objects
­Summary Vanderbilt researchers have developed a novel technology for trapping and dynamically manipulating nanoscale objects. Control over miniature objects like proteins can aid in applications such as biological sensing, single molecule analysis, and size-based sorting of nanoscale objects. Addressed Need Optical tweezers have emerged as a...
Published: 8/28/2025   |   Inventor(s):  
Keywords(s):  
Category(s): General Engineering, Microfluidics
Functional, Physiologically Accurate Resistance Blood Vessels for Drug and Artificial Tissue Development
Summary Physiologically accurate models of resistance blood vessels that are capable of vasoconstriction and vasodilation offer an excellent in vitro platform for testing drugs for vascular diseases involving smooth muscle cells. Vanderbilt researchers have developed methods to fabricate resistance blood vessels that make such a biomimetic platform...
Published: 1/30/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Microfluidics
A Novel Organs-On-Chip Platform
Summary Vanderbilt researchers have created a new multi-organs-on-chip platform that comprises Perfusion Control systems, MicroFormulators, and MicroClinical Analyzers connected via fluidic networks. The real-time combination of multiple different solutions to create customized perfusion media and the analysis of the effluents from each well are both...
Published: 7/3/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Medical Devices, Microfluidics, Research Tools, Diagnostics
Modular and Stackable Microfluidic Devices
Summary Vanderbilt researchers have invented a modular microfluidic bioreactor that can be layered and stacked to create complex organ-on-chip systems that mimic the behavior of human organ systems such as the neurovascular unit. This modular device can also be assembled from separate, functioning biolayers, and at the end of a study disassembled for...
Published: 6/17/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Microfluidics
Organ-on-a-Chip System
SummaryVanderbilt researchers have developed a group of microfluidic organ-on-chip devices that include perfusion controllers, microclinical analyzers, microformulators, and integrated microfluidic measurement chips. Together, these devices can measure and control multiple organ-on-chip systems in order to model the multi-organ physiology of humans.Addressed...
Published: 7/9/2024   |   Inventor(s):  
Keywords(s):  
Category(s): Microfluidics
Low-cost, Normally Closed Microfluidic Valve
Summary Vanderbilt researchers have developed a normally closed valve that is able to provide selective movement of small fluid quantities in a microfluidic device. The present microfluidic valve can be actuated using a simple rotating drivehead and mechanical support, greatly simplifying the valve design. Addressed Need Microfluidics is a rapidly...
Published: 6/17/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Diagnostics, Microfluidics
Rotary Planar Peristaltic Micropump (RPPM) and Rotary Planar Valve (RPV) for Microfluidic Systems
SummaryA Vanderbilt University research team led by Professor John Wikswo has developed low-cost, small-volume, metering peristaltic micropumps and microvalves. These pumps and valves can be used either as stand-alone devices incorporated into microfluidic subsystems, or as readily customized components for research or miniaturized point-of-care instruments,...
Published: 7/9/2024   |   Inventor(s): Parker Gould, Lloyd (Loi) Hoang, William Matloff, Kevin Seale, John Wikswo, Jr., Joseph Scherrer
Keywords(s):  
Category(s): Microfluidics, Medical Devices