Search Results - michele+carbone

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anti-HMGB1 antibody for mesothelioma
In the US, asbestos causes approximately 2,000 - 3,000 malignant mesothelioma deaths per year, and it contributes to an even larger number of lung carcinomas. The latency from time of exposure to tumor development potentially allows time for intervention to block the mechanism(s) that trigger asbestos-induced carcinogenesis. This invention proposes...
Published: 11/19/2021   |   Inventor(s): Haining Yang, Michele Carbone, Marco Bianchi
Keywords(s):  
Category(s): Healthcare, Therapeutic
Mesothelioma Biomarker - High Mobility Group Box 1 (HMGB1) protein as a novel, sensitive biomarker for detecting asbestos exposure and mesothelioma
Malignant mesothelioma, associated with asbestos or erionite exposure, is an aggressive and lethal cancer of the mesothelium, the protective lining that covers many internal organs, and is most commonly found in the pleura (outer lining of the lungs). The inventors discovered that misregulation of a protein called High Mobility Group Box 1 (HMGB1) is...
Published: 2/29/2024   |   Inventor(s): Haining Yang, Michele Carbone, Harvey Pass
Keywords(s): Diagnostic:Marker, Healthcare:Diagnostic Tool, Healthcare:Oncology, Screening:Detection
Category(s): Healthcare, Diagnostic, Diagnostic, Therapeutic