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Search Results - mehrdad+shadmehr
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Quantitative Detection of Protein Misfolding or Aggregation by Chemical Labeling
This invention describes methods and systems for detecting, comparing, or evaluating proteins in a folded conformation, a particular bound state, or an aggregate state, and methods and systems for comparing amounts of labeling of a protein in a natural or control conformation and a denatured conformation. The methods of this invention may be used for...
Published: 6/20/2024
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Inventor(s):
Jacob Schwartz
,
John Jewett
,
Mahta Moinpour
,
Mehrdad Shadmehr
Keywords(s):
Category(s):
Technology Classifications > Life Sciences > Biomarkers
,
Technology Classifications > Healthcare Portfolios > Neurology
,
Technology Classifications > Medical Devices > Diagnostic
Fluorogenic Diazonium-Derived Fluorophores
This technology describes various diazonium salts that can react to produce a fluorescent azobenzene compound. Background: Current iterations of fluorescent diazonium salts utilize metal catalysts to produce a reaction. However, these metal catalysts can have harmful effects in a medical setting. This invention consists of a bioorthogonal approach...
Published: 3/12/2024
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Inventor(s):
John Jewett
,
Bereketab Mehari
,
Mehrdad Shadmehr
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics > Medical Imaging
,
Technology Classifications > Life Sciences > Biologics
,
Technology Classifications > Life Sciences > Biomarkers
,
Technology Classifications > Life Sciences > Diagnostics
,
Technology Classifications > Materials > Biocompatible
,
Technology Classifications > Materials > Biomaterials
,
Technology Classifications > Research Tools > Screening assays
,
Technology Classifications > Medical Devices > Diagnostic