Search Results - jacob+schwartz

8 Results Sort By:
Therapeutic Target of Ewing Sarcoma by G-Quadruplex Binding Compound
This innovation identified lead molecules that target specific nucleic acid structures involved with forming G-Quadruplex structures. These G-Quadruplex structures are a highly stable nucleic acid fold with planar stacks of guanine tetrads which regulate genome stability, transcription, and telomere maintenance. This innovation details a therapeutic...
Published: 3/12/2026   |   Updated: 1/6/2026   |   Inventor(s): Jacob Schwartz, Haining Zhu, Ajibola Adelekun, Valery Thompson
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Oncology
Spin-polarized fusion fuel with enhanced reactivity and isotropic emission
Fusion reaction rates and the angular distribution of emitted products, such as neutrons and alpha particles, are significantly influenced by the spin states of the fuel nuclei, including deuterium, tritium, and helium-3. While the selective preparation of nuclei in specific spin states can enhance fusion reaction rates, this typically results in anisotropic...
Published: 4/7/2026   |   Updated: 7/28/2025   |   Inventor(s): Jacob Schwartz
Keywords(s):  
Category(s): Plasma/Fusion
Spin-Polarized Fuels for Enhanced Tritium Burn Efficiency in Fusion Energy Systems
Magnetic confinement fusion power plants face a fundamental challenge in efficiently utilizing tritium fuel, a critical and limited resource. While increasing tritium burn efficiency (TBE)—the fraction of injected tritium that fuses—is desirable for fuel self-sufficiency and reducing inventory, existing approaches encounter an inherent trade-off:...
Published: 7/28/2025   |   Updated: 7/28/2025   |   Inventor(s): Jason Parisi, Ahmed Diallo, Jacob Schwartz
Keywords(s): fusion
Category(s): Plasma/Fusion
Protein Structure Analysis using One-Step Tyrosine Conjugation
This invention includes methods and systems for detecting, comparing, or evaluating proteins in an folded conformation, a particular bound state, or an aggregate state, and methods and systems for comparing amounts of labeling of a protein in a natural or control conformation and a denatured conformation. The methods of this invention may be used for...
Published: 3/12/2024   |   Updated: 12/2/2020   |   Inventor(s): Jacob Schwartz, John Jewett, Mahta Moinpour
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Neurology > CNS & Neurosciences, Technology Classifications > Healthcare Portfolios > Orphan Diseases, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Protein
Detection of Protein: Nucleic Acid Interactions by Differential Chemical Conjugation
This invention features methods, systems, and compositions for detecting interactions between biomolecules. The methods or systems of the present invention may feature comparing the amount of labeling or modification of a molecule in a test sample with the amount of labeling or modification of the molecule in a control sample. For example, the method...
Published: 3/12/2024   |   Updated: 5/31/2017   |   Inventor(s): Jacob Schwartz, Mahta Moinpour
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Diagnostics
Quantitative Detection of Protein Misfolding or Aggregation by Chemical Labeling
This invention describes methods and systems for detecting, comparing, or evaluating proteins in a folded conformation, a particular bound state, or an aggregate state, and methods and systems for comparing amounts of labeling of a protein in a natural or control conformation and a denatured conformation. The methods of this invention may be used for...
Published: 6/20/2024   |   Updated: 5/31/2017   |   Inventor(s): Jacob Schwartz, John Jewett, Mahta Moinpour, Mehrdad Shadmehr
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Medical Devices > Diagnostic
Detection of Folding State of a Macromolecules by Chemical Conjugation
Methods and systems for detecting, comparing, or evaluating proteins in an folded conformation, a particular bound state, or an aggregate state, and methods and systems for comparing amounts of labeling of a protein in a natural or control conformation and a denatured conformation. The methods of the present invention may be used for a variety of applications...
Published: 3/12/2024   |   Updated: 2/17/2017   |   Inventor(s): Jacob Schwartz, Mahta Moinpour
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Biomarkers
Electrical Detector for Detecting Liquid Metal leaks
Princeton Docket # 15-3094-1 Researchers in the Department of Engineering at Princeton Plasma Physics Laboratory, Princeton University, have designed an electrical detector for detecting liquid metal leaks. Liquid metal has unique physical properties and many applications. For instance, liquid lithium is a candidate plasma facing component (PFC)...
Published: 4/23/2026   |   Updated: 10/12/2015   |   Inventor(s): Jacob Schwartz, Michael Jaworski
Keywords(s): fusion
Category(s): Mechanical/Electrical Engineering