Search Results - mark+knappenberger

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Rapid, Sensitive, LAMP Assay for Monkeypox Virus Clade Differentiation
Invention Description Orthopox monkeypox (MPXV) has recently emerged as a global viral threat with two distinct clades identified as endemic pathogens. It is estimated that 70% of the world’s population is vulnerable to infection by members of orthopoxviridae. Rapid identification of MPXV clades is critical, as Clade I infections are more clinically...
Published: 3/5/2026   |   Inventor(s): Mark Knappenberger, Karen Anderson
Keywords(s):  
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Point of Care
Switchable mRNA Expression Platform
Invention Description While recent advances have made RNA therapeutics and vaccines more mainstream, they still suffer from drawbacks including high-dosing requirements and the inability for conditional and targeted expression. Further, they can experience off-target gene expression and related side effects as well as challenges in tissue- or cell-specific...
Published: 2/26/2026   |   Inventor(s): Petr Sulc, Mark Knappenberger, Archana Kikla, Matthew Sample, Karen Anderson
Keywords(s):  
Category(s): Vaccines/Antimicrobials, Non-Cancer Therapeutics, Pharmaceuticals, Life Science (All LS Techs), Genomic Assays/Reagents/Tools
Multiplexed HLA mRNA Preparation for Downstream Sequencing
Human Leukocyte Antigens (HLA) are protein complexes residing on cell surfaces responsible for regulating immune responses. HLA haplotype sequencing is integral to the development of personalized therapies and diagnostics. It is also paramount to the understanding of T cell mediated immunity. There are over six classical major HLA loci with over 32,000...
Published: 2/13/2025   |   Inventor(s): Oliver Kask, Mark Knappenberger, Karen Anderson
Keywords(s):  
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Genomic Assays/Reagents/Tools