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Advanced hot melt extrusion (HME) technology with reduced decomposition
The technology involves using hot melt extrusion (HME) to prepare amorphous drug formulations with reduced decomposition. This method incorporates a pharmaceutically acceptable thermoplastic polymer and an organic solvent to lower processing temperatures and stress, ensuring drug stability. Background HME is a widely used technique in the pharmaceutical...
Published: 9/10/2024   |   Inventor(s): Feng Zhang, Robert Williams, Abbe Miller, Siyuan Huang
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug discovery, Life sciences > Biomaterials