Search Results - hendrik+luesch

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y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability

Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...

Published: 9/25/2023 | Inventor(s): Jianfeng Cai, Shibo JIANG, Lu LU, Songyi XUE, Xinling WANG, Lei WANG, Wei XU, Shuai XIA

Keywords(s): Drug Discovery, Immunology

Category(s): Technology Classifications > Medical > Biotechnology

Gatorbulin-1, a Microtubule-Destabilizing Agent for Disrupting Cancerous Tumors

Targets a Newly Identified Tubulin Binding Site to Destabilize Tubulin This microtubule-destabilizing agent, derived from a marine cyanobacterium, targets a new seventh tubulin-binding site and inhibits cancer cell growth. Tubulin-targeting chemotherapy is a proven successful and wide-spectrum strategy against multiple solid and liquid malignancies....

Published: 6/23/2023 | Inventor(s): Hendrik Luesch, Valerie Paul, Susan Matthew, Qi-Yin Chen, Ranjala Ratnayake

Keywords(s):

Category(s): Technology Classifications > Human Health Care > Therapeutics

Molecular Antagonist That May Be Effective Treatment for Opioid Addiction

Prevents Morphine-Seeking Behavior in Animals This molecular antagonist has been shown to prevent morphine-seeking behavior in animals and may be an effective treatment for opioid addiction in humans . The Center for Disease Control and Prevention estimates that opioid prescription misuse accounts for $78.5 billion in economic burden, and in 2019 alone,...

Published: 9/7/2022 | Inventor(s): Robert Huigens, Verrill Norwood, Hendrik Luesch

Keywords(s):

Category(s): Technology Classifications > Human Health Care > Therapeutics

Network-Coded Multiple Access

[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...

Published: 1/29/2024 | Inventor(s): Soung Chang Liew, Lu LU, Lizhao You

Keywords(s): Network Coding, Wireless Local Area Network

Category(s): Information and Communications Technology