Search Results - health+serv%2foutcomes%2fquality%2fsys+improv

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Serum Biomarker for Stratifying Patients in Septic Shock Clinical Trials
Overview: Currently, there exists no method for stratifying pediatric septic shock clinical trial candidates. Specifically, there is no way to eliminate patients that would have a high likelihood of a positive outcome with standard care from these trials. Dr. Wong at Cincinnati Children's Hospital has demonstrated that there is a marked increase...
Published: 8/20/2018   |   Inventor(s): Hector Wong
Keywords(s): 1 - Diagnostic, Diagnostic Tests, Health Serv/Outcomes/Quality/Sys Improv
Category(s): Diagnostics
Diagnostic and Prognostic for Crohn's Disease and Ulcerative Colitis
Diagnostic and Prognostic for Crohn's Disease and Ulcerative Colitis (CHMC Ref. Id: 2007-0105) Overview: Several defects in neutrophil function have been noted in Crohn's Disease (CD), including reduced phagocytosis, adhesion, chemotaxis, and oxidative burst. This has been shown to reduce neutrophil accumulation at sites of injury, promoting...
Published: 10/31/2023   |   Inventor(s): Lee Denson, Bruce Trapnell, Kanji Uchida
Keywords(s): 1 - Diagnostic, Diagnostic Tests, Genomics/Epigenomics, Health Serv/Outcomes/Quality/Sys Improv, Inflammation/Immunity/Immune Therapy, Protein Sci/Structural Bio/Medicinal Che, Systems Biology
Category(s): Diagnostics
Diagnostic and Prognostic for Crohn's Disease
Diagnostic and Prognostic for Crohn's Disease (CHMC Ref. Id: 2006-0202) Overview: Standard therapies for IBD include steroids and immunomodulators which lead to a sustained remission in approximately 50% of patients. Currently, there are no reliable predictors of response, leading Dr. Denson and colleagues to prepare and stratify patient...
Published: 2/8/2023   |   Inventor(s): Lee Denson, Bruce Aronow, Huan Xu
Keywords(s): 1 - Diagnostic, Diagnostic Tests, Genomics/Epigenomics, Health Serv/Outcomes/Quality/Sys Improv, Inflammation/Immunity/Immune Therapy, Systems Biology
Category(s): Diagnostics
Diagnosis and Prevention of Fetal Heart Disease
Diagnosis and Prevention of Fetal Heart Disease (CHMC Ref. Id: 2005-0303) Overview: This technology is a method for assessing the likelihood of the presence or formation of fetal heart disease, such as hypoplastic left heart syndrome (HLHS), in a fetus by testing for the presence of anti-strep antibodies in the mother. Applications: Prenatal...
Published: 8/20/2018   |   Inventor(s): Pirooz Eghtesady
Keywords(s): 1 - Diagnostic, Diagnostic Tests, Health Serv/Outcomes/Quality/Sys Improv
Category(s): Diagnostics