Search Results - guangtao+(george)+zhang

6 Results Sort By:
Sensitizing Cancer Cells to DNA Targeted Therapies
Abstract: Chk2 is a protein kinase activated in response to DNA double strand breaks. In normal tissues, Chk2 phosphorylates and thereby activates substrates that induce programmed cell death, or apoptosis, via interactions with p53, E2F1, PML proteins. In cancer tissues, where apoptosis is suppressed, Chk2 phosphorylates and inactivates cell cycle...
Published: 4/8/2024   |   Inventor(s): Yves Pommier, Dominic Scudiero, Christopher Self, Robert Shoemaker, David Waugh, Guangtao (George) Zhang, John Cardellina, Michael Currens, Andrew Collasanti, Charles Cook, Andrew Jobson, Sudhir Kondapaka, George Lountos
Keywords(s): Anti-cancer Therapeutic, Chk2 Inhibitors, Sensitizing Agent for current DNA-damaging cancer therapeuti
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics
Method for 3D Nonlinear Structured Illumination Super-resolution Imaging
Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...
Published: 4/3/2023   |   Inventor(s): Leilei Peng, Yu Li, Han Zhang
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
Self-Adaptive Control And Optimization Of Ultrafiltration
UC Case No. 2016-159SUMMARYUCLA researchers in the Department of Chemical and Biomolecular engineering have developed a novel UF-RO system.BACKGROUNDUltrafiltration (UF) is the process of membrane-based removal of particles. It is used in a number of different industries such as food production, water treatment, desalination etc. In particular, in water...
Published: 7/19/2023   |   Inventor(s): Yoram Cohen, Panagiotis Christofides, Anditya Rahardianto, Han Gu, Larry Xingming Gao
Keywords(s): Energy & Water
Category(s): Energy & Environment > Water Monitoring & Treatment, Materials > Water Treatment
2011-138 Integrated Ultrafiltration and Reverse Osmosis Process and System
SUMMARYProfessor Cohen and colleagues have developed a compact and self-adaptive integrated water ultrafiltration and reverse osmosis (UF/RO) process and system. Designed to produce up to 18,000 gallons of drinking quality water per day with no intermediate tanks between UF and RO or for UF backwash, the system can be further expanded for even larger...
Published: 7/19/2023   |   Inventor(s): Yoram Cohen, Panagiotis Christofides, Anditya Rahardianto, Alex Bartman, Aihua Zhu, Han Gu, Larry Xingming Gao
Keywords(s):  
Category(s): Materials > Functional Materials
An Osteoinductive Composite Scaffold Material Incorporating Phytoestrogenic and Osteoinductive Molecule Icaritin for Treatment of Bone Defect
 
Published: 7/27/2016   |   Inventor(s): Ling Qin, Xiao Hong Wang, Xin Hui Xie, Xin Luan Wang, Ge Zhang, Xin Sheng Yao, Kwok Sui Leung, Kwok Pui Fung, Yong Nian Yan, Jiang Peng, Kai Ming Chan, Chun Yiu Cheng, Leung Kim Hung
Keywords(s):  
Category(s): Therapeutics
Preparation of a targeted delivery system for osteogenic siRNA
 
Published: 3/16/2022   |   Inventor(s): Ling QIN, Ge Zhang, Heng Wu, Leung Kim Hung
Keywords(s):  
Category(s): Therapeutics