Search Results - george+coukos

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Universal cancer vaccine targeting tumor vasculature
A DNA vaccine targeting tumor endothelial marker 1 (TEM1) that allows to prevent and delay tumor progression without adverse effect on physiologic angiogenesis Technology Overview: Immunization against antigens specifically expressed on tumor vasculature is a very attractive immunotherapy options due to its ability to prevent solid tumor growth....
Published: 6/21/2024   |   Inventor(s): George Coukos
Keywords(s): Oncology
Category(s): Technology Classifications > Vaccines
Enhancing the Efficacy of Tumor Immunotherapy by Targeting Endothelin Receptor B
Antagonism of Endothelin Receptor B (ETRB) increases intratumoral T cell homing to tumors and enables tumor response to otherwise ineffective immunotherapy Problem: In spite of generating a tangible antitumor cellular immune response in peripheral blood, tumor vaccines have proven largely ineffective for treatment of solid tumors. The success of...
Published: 1/10/2024   |   Inventor(s): George Coukos
Keywords(s): Immunotherapy, Oncology
Category(s): Technology Classifications > Vaccines