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Assay to Screen Anti-metastatic Drugs
Abstract: Scientists at the NCI developed a research tool, a murine cell line model (JygMC(A)) with a reporter construct, of spontaneous metastatic mammary carcinoma that resembles the human breast cancer metastatic process in a triple negative mammary tumor. The assay is useful for screening compounds that specifically inhibit pathways involved in...
Published: 8/13/2024   |   Inventor(s): Nadia Castro, David Salomon, Frank Cuttitta
Keywords(s): ANGIOGENESIS, Cell line, Metastasis, Triple Negative Breast Cancer, tumorigenesis
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Research Materials