Inteum Company
Links
seedsprint
Visible Legacy
RSS
News & Resources
Inteum Company News
Inteum Library
Subscribe
Search Results - eric+witze
2
Results
Sort By:
Published Date
Updated Date
Title
ID
Descending
Ascending
Pyrazole Derivatives for the Treatment of Lung Cancer Tumors
A class of pyrazole derivatives that inhibit palmitoyl-transferases, resulting in increasing cancer cell responsiveness to epidermal growth factor receptor inhibitor and KRas mutant lung cancer growth inhibition as a single agent. Problem: Pancreatic and lung cancers are largely driven by either Epidermal growth factor receptor (EGFR) mutation KRAS...
Published: 5/31/2024
|
Inventor(s):
George Burslem
,
Eric Witze
Keywords(s):
Oncology
,
Small Molecule
Category(s):
Technology Classifications > Therapeutics
Novel Compounds for Sensitization of Cancer Cells to EGFR Inhibitors
Method allowing to increase sensitivity and/or overcome resistance to EGFR inhibitors in cancer cells through inhibition of palmitoyltransferase DHHC20. Problem: Inappropriate activation of the epidermal growth factor receptor (EGFR) contributes to a variety of human malignancies and correlates with poor prognosis and resistance to therapy. Whereas...
Published: 1/10/2024
|
Inventor(s):
Eric Witze
Keywords(s):
Oncology
Category(s):
Technology Classifications > Therapeutics