Search Results - eric+hostetler

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EGFRvIII Antibodies for the Treatment of Human Cancer
Abstract: Epidermal growth factor receptor variant III (EGFRvIII) is a variant of EGFR that is an excellent target for immunotherapy because of its expression in cancer cells and not in normal cells.  Inventors from the National Cancer Institute (NCI) have isolated seven mouse monoclonal antibodies that bind to the human EGFRvIII but not wildtype EGFR....
Published: 4/8/2024   |   Inventor(s): David Fitzgerald, Antonella Antignani, Eric Ho, Robert Sarnovsky
Keywords(s): ADC, Antibody-drug Conjugate, CAR, chimeric antigen receptor, EGFR, EGFRvIII, Epidermal Growth Factor Receptor, Epidermal growth factor receptor variant III, FitzGerald, Recombinant Immunotoxins, RITs
Category(s): Application > Therapeutics, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing
Segmented Flow for a Continuous Flow Microwave Reactor
Technology Description This invention is a continuous, segmented flow reactor system and method for the production of high quality NCs with microwave radiation. The system for NCs synthesis consists of an NC precursor configured to include an NC precursor solution with the ability to include a microwave reactor, segmentation fluid source, or other configurations...
Published: 5/10/2021   |   Inventor(s): Gregory Herman, Brian Paul, Chih-Hung Chang, Ki-Joong Kim, Richard Oleksak, Padmavathi Chandran, Eric Hostetler, Brendan Flynn, Daniel Peterson, Bob Fitzmorris, Gustavo Albuquerque
Keywords(s): Advanced Technology and Manufacturing Inst. (ATAMI), Chemicals / Chemical Engineering, Computer Software, Materials Science, Nanotechnology, Photovoltaics
Category(s): Engineering