Search Results - david+ostrov

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Method for Treating Melanoma using an Inhibitor of an Atypical Protein Kinase C (PKC)
­Advantages: Effectively decreases melanoma cell proliferation and suppresses tumor migration and metastasis. Promotes cancer cell death, specifically targeting melanoma cells and sparing healthy melanocytes. The method not only treats melanoma by targeting atypical PKC isoforms but also utilizes PKC-ι and PKC-ζ levels as biomarkers...
Published: 8/16/2024   |   Inventor(s): Mildred Acevedo-Duncan, Wishrawana Ratnayake, David Ostrov
Keywords(s): Cancer Treatment Melanoma
Category(s): Technology Classifications > Cancer > Cancer Treatment Melanoma, Technology Classifications > Cancer > Cancer Diagnostics, Technology Classifications > Cancer > Cancer Treatment Adenocarcinomas, Technology Classifications > Medical > Therapeutics, Technology Classifications > Cancer
A Method of Treating Colorectal Cancer Using Atypical Protein Kinase C Inhibitors
Competitive Advantages Reduces colorectal cancer cell growth and proliferation Does not harm healthy cells Applicable as anti-atypical PKC therapy Summary USF scientists have discovered that by inhibiting PKC-iota and PKC-zeta with certain drugs (ACPD, DNDA and ICA-1), a significant decrease in cancer cell proliferation is shown. Furthermore,...
Published: 6/14/2023   |   Inventor(s): Mildred Acevedo-Duncan, Anisul Islam, David Ostrov
Keywords(s):  
Category(s): Technology Classifications > Cancer
Sigma Receptor Ligands for COVID-19 Viral Infection Treatment
Anti-Viral Binding Compound Treats and Prevents COVID-19 Infection and Symptoms A compound that binds to sigma receptors can treat and prevent viral infections, such as SARS-CoV-2 (COVID-19), and their symptoms. COVID-19 was first detected in December 2019 in Wuhan, China. In January 2020, the first cases in the United States (U.S.) were reported....
Published: 8/5/2022   |   Inventor(s): Christopher McCurdy, Michael Norris, David Ostrov
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics