Search Results - daniel+von+hoff

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2-Aryl-Pyridylazoles for the Treatment of Solid Tumors such as Pancreatic Cancer
University of Arizona researchers have identified two potent small molecules that target a common mutation found in pancreatic cancer cells with high specificity and induce cell death. These compounds are genotype specific for the DPC4 mutation associated with cancer phenotypes and, compared to available treatments, are significantly more potent and...
Published: 11/16/2023   |   Inventor(s): Robert Dorr, Gary Flynn, Haiyong Han, Meredith Henderson, Laurence Hurley, Yeng Jeng Shaw, Daniel Von Hoff
Keywords(s):  
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Small Molecules
Methods for identifying and treating pancreatic cancer with ROCK1 therapeutic target
Researchers at TGen have developed a method for identifying and treating pancreatic cancer. Through the identification of the ROCK1 gene as a therapeutic target, pancreatic cancer can be detected and tumor cell proliferation and migration can be inhibited using the inventive methods.Pancreatic cancer is a prevalent cause of tumor related deaths in...
Published: 6/24/2024   |   Inventor(s): Haiyong Han, Clifford Whatcott, Daniel Von Hoff, Michael Barrett
Keywords(s):  
Category(s): Therapeutics