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2-Aryl-Pyridylazoles for the Treatment of Solid Tumors such as Pancreatic Cancer

University of Arizona researchers have identified two potent small molecules that target a common mutation found in pancreatic cancer cells with high specificity and induce cell death. These compounds are genotype specific for the DPC4 mutation associated with cancer phenotypes and, compared to available treatments, are significantly more potent and...

Published: 11/16/2023 | Inventor(s): Robert Dorr, Gary Flynn, Haiyong Han, Meredith Henderson, Laurence Hurley, Yeng Jeng Shaw, Daniel Von Hoff

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Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Small Molecules