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Allosteric Modulation of Muscarinic Acetylcholine Receptor for Treatment of Neurological Disorders
Project ID: D2022-18 Muscarinic acetylcholine receptors (mAChRs) are G protein-coupled receptors that are located in the cell membranes of neurons and mediate the effects of the neurotransmitter acetylcholine (ACh). Each mAChR forms a complex with intracellular G proteins that, when activated, produce an intracellular signaling cascade. Each mAChR...
Published: 4/6/2026   |   Updated: 8/18/2023   |   Inventor(s): William Messer, Hazel Cunningham, Corey Widman, John Ellis, Isaac Schiefer, Gina Kaup
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Category(s): Neuroscience