Search Results - christopher+miranda

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Photoacoustic Microscopy Platform
Optical characterization of cells and tissues is necessary to understanding physiological mechanisms. However, current optical imaging techniques have limited imaging depth, often because of strong optical scattering. Photoacoustic imaging (PAI) is a powerful technique which combines the high contrast of optical imaging with the high spatial resolution...
Published: 1/19/2024   |   Inventor(s): Barbara Smith, Ethan Marschall, Joel Lusk, Christopher Miranda
Keywords(s):  
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Manufacturing/Construction/Mechanical, Medical Devices
Photoacoustic Cuvette Platform
Cuvettes, used to measure the absorbance of light in spectroscopy, are designed to hold a small volume of liquid sample and are optically transparent to allow light to pass through the sample. They are highly useful in spectrophotometry, fluorescence spectroscopy, UV spectroscopy and photoacoustic spectroscopy. While the optical characteristics of the...
Published: 1/19/2024   |   Inventor(s): Barbara Smith, Ethan Marschall, Christopher Miranda
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Medical Devices, Life Science (All LS Techs), Manufacturing/Construction/Mechanical, Applied Technologies
Non-contact, All Optical, Photoacoustic Microscopy
Invention Description Photoacoustic microscopy (PAM), the imaging technique that generates acoustic waves caused by thermal expansion due to optical absorption, has been successfully utilized to provide absorption-based contrast at unparalleled depths. Recent advancements in PAM have enabled contrast-free image reconstructions of subcellular components...
Published: 2/23/2023   |   Inventor(s): Christopher Miranda, Barbara Smith
Keywords(s):  
Category(s): Life Science (All LS Techs), Medical Devices, Medical Imaging
Novel Ion Indicator Systems
The activity of neurons has long been studied to characterize and understand neurological activity. Neurological activity is directly related to changes in membrane potential due to ion flux across the neuronal membrane. Imaging of this ion flux can provide insight into neural activity and enable research into function and disorders. Current approaches...
Published: 2/23/2023   |   Inventor(s): Christopher Miranda, Barbara Smith
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Life Science (All LS Techs), Medical Devices, Medical Imaging, Neurodegenerative Disease Technologies
Novel Ion Indicator Systems
The activity of neurons has long been studied to characterize and understand neurological activity. Neurological activity is directly related to changes in membrane potential due to ion flux across the neuronal membrane. Imaging of this ion flux can provide insight into neural activity and enable research into function and disorders. Current approaches...
Published: 2/23/2023   |   Inventor(s): Barbara Smith, Christopher Miranda, Madeleine Howell, Joel Lusk
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Medical Imaging, Life Science (All LS Techs), Medical Devices, Neurodegenerative Disease Technologies
Deep Brain Stimulation with Imaging Capabilities
Deep brain stimulation (DBS) is a procedure that is used to treat intractable pain as well as many movement disorders and the applications are continually expanding. DBS uses electrical current to stimulate brain tissue and modulate the communication between nerves. Currently, when DBS is performed, it is done with little visual guidance, and no real-time...
Published: 2/23/2023   |   Inventor(s): Christopher Miranda, Barbara Smith
Keywords(s):  
Category(s): Life Science (All LS Techs), Medical Devices, Medical Imaging, Neurodegenerative Disease Technologies