Search Results - cholera

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Tryptophan as a Functional Replacement for ADP-ribose-arginine in Recombinant Proteins
Bacterial toxins such as cholera toxin and diphtheria toxin catalyze the ADP-ribosylation of important cellular target proteins in their human hosts, thereby, as in the case of cholera toxin, irreversibly activating adenylyl cyclase. In this reaction, the toxin transfers the ADP-ribose moiety of Nicotinamide Adenine Dinucleotide (NAD) to an acceptor...
Published: 10/28/2024   |   Inventor(s): Joel Moss
Keywords(s): cholera, DB3XXX, DBXXXX, DIPHTHERIA, DXXXXX
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Therapeutics
Clones Encoding Mammalian ADP-Ribosylarginine Hydrolases
ADP-ribosylation of arginine residues in proteins may be involved in cell adhesion and is crucial for the action of cholera toxin and E. coli heat-labile enterotoxin, agents involved in the pathogenesis of cholera and traveller's diarrhoea, respectively. ADP-ribosylation is reversed by ADP-ribosylarginine hydrolases, which cleave the ADP-ribose-arginine...
Published: 4/8/2024   |   Inventor(s): Joel Moss, Sally Stanley, Maria Nightingale, James Murtagh, Lucia Monaco, Tatsuyuki Takada
Keywords(s): cholera, Cholera (Vibrio cholerae), DA3XXX, DAXXXX, DB3XXX, DBXXXX, DXXXXX
Category(s): Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Infectious Disease, Application > Therapeutics
Smartphone Software to Manage Electronic Patient Data Without Internet Access
Provides a Platform to Locate and Identify Patients and Maintain Medical Records When Operating Offline, During Disease Outbreaks, or During Natural DisastersThis smartphone data-collection software optimizes medical providers' access to and management of patient medical records, integrate diagnostics, and automates evidence-based treatment guidelines...
Published: 6/27/2021   |   Inventor(s): Eric Nelson, Stace Maples
Keywords(s): cholera, decision-support, logistics, outbreak responder, rehydration calculator
Category(s): Technology Classifications > Software > Mobile Apps