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Single viral vector for expression of both CAR/TCR and immune modulators for cancer immunotherapy
A single lentiviral vector system as an expression platform for constitutive immune receptor expression and inducible antigen-dependent immunomodulatory molecule expression in primary immune cells for enhanced immunotherapy efficacy Problem: Adoptive cancer immunotherapy, like chimeric antigen receptor T cell (CAR T) therapy, has had extraordinary...
Published: 11/11/2024   |   Inventor(s): Daniel Powell, Anze Smole, Avery Posey
Keywords(s): CAR T-cell Enhancing Technology
Category(s): Technology Classifications > Research Tools & Reagents, Technology Classifications > Therapeutics