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Benzodiazepinone-derived Inhibitors of EGFR and HER2
A class of benzodiazepinone-derived molecules, inhibitors of both triple mutant EGFR and HER2, for cancer therapeutics or biochemical research tools. Background: Inhibition of epithelial growth factor receptor (EGFR) as a non-small cell lung cancer (NSCLC) therapeutic is not a new concept, but 75% of patients die within five years of diagnosis. As...
Published: 5/13/2025   |   Inventor(s): David Heppner, Stefan Laufer, Florian Wittlinger, Blessing Ogboo, Calvin Pham, Alexander Rasch
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Materials and Chemicals