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Compositions and methods of chimeric autoantibody receptor T cells expressing extended phospholipase A2 receptor fragments
Brief Description: The invention includes compositions comprising at least one chimeric autoantibody receptor (CAAR) specific for an anti-phospholipase A2 receptor (PLA2R) autoantibody-based B cell receptor (BCR), polynucleotides encoding the CAAR, vectors comprising a polynucleotide encoding the CAAR, and recombinant cells (e.g., T cells) comprising...
Published: 8/19/2025   |   Inventor(s): Aimee Payne, Baomei Wang
Keywords(s): Cell Therapy, Immunotherapy, Nephrology and Urology
Category(s): Technology Classifications > Therapeutics