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Search Results - abby+parrill-baker
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Inhibitors of Autotaxin for Drug Resistant Cancer Stem Cells and Fibrotic Diseases
The Technology Solution: Autotaxin (ATX, NPP2) is a member of the nucleotide pyrophosphate phosphodiesterase enzyme family. ATX catalyzes the hydrolytic cleavage of lysophosphatidylcholine (LPC) that leads to the generation of the growth factor-like lipid mediator lysophosphatidic acid (LPA). ATX stimulates the motility of tumor cells and has angiogenic...
Published: 10/17/2024
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Inventor(s):
Duane Miller
,
Gabor Tigyi
,
Souvik Banerjee
,
Abby Parrill-Baker
Keywords(s):
Category(s):
Human Health