Method and Apparatus for Generating Anti-Cancer Substances In Situ

­Advantages:

  • Targeted and minimally invasive treatment, reducing damage to healthy tissues and systemic side effects.
  • Enhanced drug delivery with localized synthesis, increasing drug concentration at the tumor site.
  • Potential for improved patient outcomes due to higher drug concentration and focused cancer cell destruction.

Summary:

This technology aims to address the limitations of conventional cancer treatments, characterized by systemic side effects and inadequate localized drug delivery. It presents a wireless powered implantable microdevice, called micro cisplatin synthesizer, designed to generate an anticancer substance within the living body by utilizing an implanted device activated through an externally generated ultrasound. The device includes an electric energy conversion module, at least one electrode pair causing electrolysis in the body fluid, and a light emission module that emits light to the electrolysis by-product. With improved energy efficiency and the capability to produce a sufficient amount of anticancer agents (i.e., cisplatin), this innovative approach enables targeted and minimally invasive anticancer treatment, potentially leading to enhanced patient outcomes and advancements in cancer therapy. 

Illustration of the anticancer substance generator 100, which is inserted into the hepatic artery. This generator locally produces an anticancer substance by receiving an external signal generated by the signal generator 200. The signal, such as an ultrasonic signal, is converted to electric energy by the anticancer substance generator 100, initiating a chemical reaction through electrolysis within the living body.

Desired Partnerships:

  • License
  • Sponsored Research
  • Co-Development
Patent Information: