Search Results - yuji+yamaguchi

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Method To Treat Numerous Dermatological Conditions
Abstract: The National Cancer Institute's Laboratory of Cell Biology is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize the use of DKK1 to treat abnormal pigmentation of the skin or to regulate hair growth. Palmoplantar skin is found on a limited number of...
Published: 5/21/2024   |   Inventor(s): Vincent Hearing, Yuji Yamaguchi, Thierry Passeron
Keywords(s): Dickkopf 1, Dkk1, palmoplantar fibroblasts, WNT
Category(s): Application > Therapeutics, TherapeuticArea > Dermatology, Collaboration Sought > Licensing
Bile Acids and Other Agents that Modulate the Gut Microbiome for the Treatment of Liver Cancer
Abstract: Primary liver tumors and secondary hepatic malignancies are among the leading causes of cancer-related deaths. Liver metastases account for 95% of all hepatic cancers, and the liver is the most common site for organ metastasis in the body. The gut microbiome serves an important role in antitumor immunity regulating the efficacy of chemo- and...
Published: 4/8/2024   |   Inventor(s): Tim Greten, Chi Ma
Keywords(s): Bile Acid, Greten, Liver cancer, Natural Killer T Cells, NKT cells
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Therapeutics, Collaboration Sought > Licensing
Production of cyclopeptibodies with high target affinity and specificity that can be used as a replacement for antibodies
Background Antibodies find widespread use as therapeutic agents and for diagnostic, imaging, and immunodetection applications. Major limitations of antibodies, however, are their complex structure, limited stability, poor tissue penetration, complex manufacturing process, and associated high costs of production. Despite their numerous and important...
Published: 5/7/2024   |   Inventor(s): Rudi Fasan, Yu Gu
Keywords(s):  
Category(s): Therapeutic