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A multiplexed CRISPR genome editing platform for simultaneous gene disruption in neurons
SPADA is a CRISPR-based genome editing system that uses engineered viruses to efficiently and specifically disrupt multiple genes in targeted brain cells, enabling precise modeling of complex genetic brain disorders in animals. Background The field of neurogenetics relies heavily on genome editing to understand the mechanisms of complex psychiatric...
Published: 4/27/2026   |   Updated: 4/27/2026   |   Inventor(s): Lief Fenno, Yeonha Ju
Keywords(s):  
Category(s): Life sciences, Life sciences > Research tools > Tool/assay/screening platform