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Search Results - vladyslav+nazarenko
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Tumor-pH–Triggered Doxorubicin Prodrug with On-Demand Shelf-Stable Precursor
This invention introduces a small-molecule doxorubicin prodrug that remains inert in blood and rapidly activates in the mildly acidic tumor microenvironment. Featuring a shelf-stable maleimide pre-prodrug that converts on demand to the ultra-acid-labile DMA form, it enables targeted chemotherapy with improved selectivity, scalable synthesis, and reduced...
Published: 10/10/2025
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Inventor(s):
Ming An
,
Lan Yao
,
Vladyslav Nazarenko
Keywords(s):
Technologies
Category(s):
Campus > Binghamton University