Search Results - vision+loss

3 Results Sort By:
Gene Augmentation Therapy for Usher Syndrome 1B (UCLA Case No. 2023-138)
UCLA researchers in the Department of Ophthalmology have developed a novel approach to cure Usher Syndrome 1B. BACKGROUND: Usher syndrome is defined as a condition whose major symptoms are deafness or hearing loss, and an eye disease called retinitis pigmentosa (RP), which affects vision. The ear-related effects of Usher’s disease are caused...
Published: 9/15/2023   |   Inventor(s): David Williams
Keywords(s): Gene delivery, Genetic Disease, Hearing loss, Usher syndrome, Vision loss
Category(s): Therapeutics > Gene Therapy And Editing
Bone Marrow Mesenchymal Stem Cell (BMSC)-Derived Exosomes for the Treatment of Glaucoma
Abstract: Glaucoma is one of the world’s leading causes of irreversible blindness. There is no cure and vision lost from glaucoma cannot be restored. Glaucoma is associated with fluid build-up in the eye resulting in an increased intraocular pressure (IOP). The pressure may cause damage to the optic nerve and lead to progressive degeneration of retinal...
Published: 4/8/2024   |   Inventor(s): Stanislav Tomarev, Benjamin Mead
Keywords(s): Degenerative Ocular Disease, Exosomes, GLAUCOMA, National Eye Institute, NEI, Neuroprotection, Retinal Ganglion Cell Loss, RGC, Tomarev, Vector Encoding miRNA, Vision Loss
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Opthamology, TherapeuticArea > Eye / Ear / Nose / Throat
Method for Reproducible Differentiation of Clinical Grade Retinal Pigment Epithelium Cells
Abstract: The retinal pigment epithelium (RPE) is a cell monolayer with specialized functions crucial to maintaining the metabolic environment and chemistry of the sub-retinal and choroidal layers in the eye. Damage or disease causing RPE cell loss leads to progressive photoreceptor damage and impaired vision. Loss of RPE is observed in many of the...
Published: 4/8/2024   |   Inventor(s): Kapil Bharti
Keywords(s): Age Related Macular Degeneration, AMD, Best Disease, Bharti, Human Induced Pluripotent Stem Cells, Human Retinal Pigment Epithelial Cells, IPSCS, National Eye Institute, National Institute of Arthritis and Muscoskeletal and Skin D, NEI, NIAMS, Photoreceptor, Retinal Degenerative Diseases, RPE, STEM CELLS, Vision Loss
Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Opthamology, TherapeuticArea > Eye / Ear / Nose / Throat, Collaboration Sought > Licensing