Search Results - therapeutics+%3e+metabolism+and+endocrinology

30 Results Sort By:
Combination of Insulin-like Growth Factor-1 Receptor (IGF1R) or Insulin Receptor Inhibitors with Immune Checkpoint Inhibitors in Management of Triple-Negative Breast Cancer (UCLA Case No. 2020-872)
UCLA researchers in the Department Joe C. Wen School of Nursing have developed a novel targeted therapy for triple-negative breast cancer with a potential synergy with immunotherapy. BACKGROUND: Triple-negative breast cancer (TNBC) accounts for about 10-15% of women with breast cancer (BC), but its mortality rate is disproportionally high, causing...
Published: 10/6/2025   |   Inventor(s): Nalo Hamilton
Keywords(s):  
Category(s): Therapeutics > Oncology, Therapeutics > Oncology > Oncology Immunotherapy, Therapeutics > Metabolism And Endocrinology, Diagnostic Markers > Cancer
A Microbial Metabolite That Promotes Stress/Anxiety (UCLA Case No. 2026-007)
Contact UCLA Technology Development Group to learn more.
Published: 9/19/2025   |   Inventor(s): Elaine Hsiao
Keywords(s):  
Category(s): Therapeutics > Psychiatry And Mental Health, Therapeutics > Metabolism And Endocrinology
Food Derived Compounds for Improving Cognitive Health (UCLA Case No. 2025-279)
Contact UCLA Technology Development Group to learn more.
Published: 9/18/2025   |   Inventor(s): Arpana Church, Jennifer Labus
Keywords(s):  
Category(s): Therapeutics > Metabolism And Endocrinology, Therapeutics > Gastroenterology
Glucagon Conjugated Trehalose Diblock Copolymers and Methods of Use (UCLA Case No. 2024-283)
UCLA researchers from the Department of Medicine-Endocrinology have formulated a novel nanoparticle for management of hypoglycemia that can efficiently deliver glucagon, while also allowing for long-term stabilization and storage. BACKGROUND: Hypoglycemia is a condition characterized by abnormally low blood glucose levels, posing a significant risk...
Published: 12/9/2025   |   Inventor(s): Heather Maynard
Keywords(s):  
Category(s): Platforms > Drug Delivery, Chemical > Polymers, Therapeutics > Metabolism And Endocrinology
Compositions and Methods for Boosting Stress, Psychological, and Cognitive Related Resilience (UCLA Case No. 2024-281)
UCLA researchers have identified a novel high resilience brain gut microbiome phenotype and biological pathways by which stress related disorders may be prevented or reduced. BACKGROUND: In the United States, stress-related health care costs and lost productivity exceed $300 billion annually, underscoring the urgent need to improve resilience: the...
Published: 11/25/2025   |   Inventor(s): Arpana Church, Tien Dong
Keywords(s):  
Category(s): Therapeutics > Gastroenterology, Therapeutics > Metabolism And Endocrinology
Targeting the Bile Acid Pathway to Treat Cardiometabolic Disease (UCLA Case No. 2024-146)
UCLA researchers from the Department of Medicine and Division of Cardiology have identified target enzymes involved in bile acid synthesis and developed methods to improve disease outcomes in fatty liver and atherosclerosis. BACKGROUND: Dietary fat is an essential, energy-dense nutrient necessary for survival. To support this, the intestinal system...
Published: 7/17/2025   |   Inventor(s): Thomas Vallim
Keywords(s):  
Category(s): Life Science Research Tools > Screening Libraries, Therapeutics > Gastroenterology, Therapeutics > Metabolism And Endocrinology, Life Science Research Tools > Research Methods, Therapeutics > Cardiovascular
Gut Bacterial Detoxification of Methylmercury (UCLA Case No. 2023-188)
UCLA researchers from the Department of Integrative Biology and Physiology have developed a microbiome-based therapy for methylmercury detoxification, leveraging a genetically engineered probiotic that neutralizes methlymercury in the gut prior to systemic absorption with potential applications in acute detoxification, preventative healthcare, and environmental...
Published: 8/15/2025   |   Inventor(s): Elaine Hsiao
Keywords(s):  
Category(s): Therapeutics > Gastroenterology, Therapeutics > Metabolism And Endocrinology
Fish Oil Plus Diet for Prostate Health (UCLA Case No. 2024-092)
UCLA researchers from the Department of Urology have identified a dietary intervention that may slow prostate cancer progression, offering a promising accessible, safe, and non-invasive approach to managing prostate health. BACKGROUND: Prostate cancer is the second most commonly diagnosed cancer in the United States and the fifth leading cause of death...
Published: 7/17/2025   |   Inventor(s): William Aronson
Keywords(s):  
Category(s): Therapeutics > Oncology, Therapeutics > Metabolism And Endocrinology
KHK Inhibitors as Agents for the Treatment of Cancer and Metabolic Syndrome (UCLA Case No. 2021-222)
UCLA researchers in the Department of Chemistry and Biochemistry have synthesized novel KHK inhibitors that can result in anticancer drugs targeting cancer metabolism. BACKGROUND: Fructose is a naturally occurring sugar found in fruits and vegetables, and is an integral part of the human diet. In comparison to its functional isomer, glucose, which...
Published: 7/17/2025   |   Inventor(s): Heather Christofk, Michael Jung
Keywords(s): Cancer, cancer metabolism, metabolism, Oncology (Small Molecules, Peptides and Antibodies), small molecules
Category(s): Therapeutics > Oncology, Therapeutics > Metabolism And Endocrinology
Manipulating the Gut Microbiome To Modify Host Eating Behavior (UCLA Case No. 2024-181)
UCLA researchers from the Department of Integrative Biology & Physiology have identified aspects of gut microbiome metabolism that affect host eating behavior, leading to possible microbiome therapies for appetite regulation. BACKGROUND: The microbiome consists of all microbes within the human body and has recently been shown to influence human...
Published: 7/17/2025   |   Inventor(s): Elaine Hsiao
Keywords(s):  
Category(s): Therapeutics > Gastroenterology, Therapeutics > CNS and Neurology, Therapeutics > Metabolism And Endocrinology
1 2 3