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Tetrahydropyrimidine Lipids for mRNA delivery
Title: Tetrahydropyrimidine Lipids for mRNA Delivery Tech ID: 2025-001 Status: Active Category: Nucleic Acid Therapeutics, Biotechnology, and Drug Delivery Technology Executive Statement: Innovative THP ionizable lipids enhance the efficiency, stability, and safety of mRNA delivery for advanced therapies. Description: Tetrahydropyrimidine...
Published: 7/17/2026   |   Updated: 7/17/2026   |   Inventor(s): Chandrabali Bhattacharya, Ivan Isaac
Keywords(s):  
Category(s): Technology Classifications > Therapeutics, Pharmaceuticals, Drug Delivery, Technology Classifications > Life Sciences
Green Synthesis of Unsymmetrical Phosphorous Disulfides
Title: Green Synthesis of Unsymmetrical Phosphorous Disulfides Tech ID: 2024-005 Status: Active Category: Green Chemistry and Synthetic Organic Chemistry Executive Statement: A sustainable, mild, and additive-free method for synthesizing unsymmetrical phosphorous disulfides using renewable solvents. Description: This technology introduces...
Published: 7/17/2026   |   Updated: 7/17/2026   |   Inventor(s): Jun Yong Kang, Jeffrey Ash
Keywords(s): Chemistry
Category(s): Technology Classifications > Chemistry, Technology Classifications > Therapeutics, Pharmaceuticals, Drug Delivery
New Synthetic Routes toward CBB3001 and Their Derivatives
Title: New Synthetic Routes toward CBB3001 and Their Derivatives Tech ID: 2024-004 Status: Active Category: Chemistry, Biochemistry, Pharmaceutical Development Executive Statement: Efficient synthetic methods for producing anti-cancer agents based on CBB3001 and its derivatives. Description: This technology introduces novel and optimized...
Published: 7/17/2026   |   Updated: 7/17/2026   |   Inventor(s): Jun Yong Kang, Jeffrey Ash, Citlally Lopez
Keywords(s):  
Category(s): Technology Classifications > Chemistry, Technology Classifications > Therapeutics, Pharmaceuticals, Drug Delivery
Modulation and Utility of DCAF10-associated CRL4 Ubiquitin Ligase Complexes Targeting Proteins for Proteolysis
This technology utilizes the CRL4-DCAF10 ubiquitin ligase complex to target and tag specific proteins for proteasomal degradation. By using chemical inhibitors and engineered PROTAC molecules, the system recruits target proteins to catalyze their destruction and control cellular protein levels. This mechanism provides a powerful platform for drug discovery...
Published: 7/17/2026   |   Updated: 7/17/2026   |   Inventor(s): Hui Zhang
Keywords(s):  
Category(s): Technology Classifications > Therapeutics, Pharmaceuticals, Drug Delivery, Technology Classifications > Chemistry
To develop a serum-based assay for leaky gut-driven neuroinflammation.
This novel, serum-based bioassay measures systemic inflammatory potential linked to intestinal permeability ("leaky gut"). Using cultured macrophages as biosensors, the assay detects inflammasome activation triggered by compromised gut barriers. The resulting signal serves as a predictive biomarker for early-stage neuroinflammation, particularly...
Published: 7/27/2026   |   Updated: 7/17/2026   |   Inventor(s): Prasun Guha
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Therapeutics, Pharmaceuticals, Drug Delivery
Third Generation Inhibitors *Supplement IDF
Inventor Ernesto Abel-Santos: Expertise includes: Bioorganic Chemistry, Enzymology, Bacterial Spore Germination, Bioterrorism The Invention: In an effort to study inhibitors of C. difficile spore germination, we recently found a set of compounds that have strong anti-germination activity in multiple strains. These compounds (see supplemental section...
Published: 1/27/2025   |   Updated: 4/9/2024   |   Inventor(s): Ernesto Abel-Santos, Chris Yip, Jaqueline Phan
Keywords(s):  
Category(s): All, Technology Classifications > Therapeutics, Pharmaceuticals, Drug Delivery, Technology Classifications > Chemistry
Low-cost gamma-ray detector for nuclear radiation remote sensing
The Invention: The innovation provides a method for remotely detecting gamma radiation emitted from a nuclear source. Gamma detection represents the prevalent approach to radiation detection. Currently, gammas must navigate toward the interaction zone within a physical detector (crystal) that possesses finite dimensions. In this development, a continuous...
Published: 6/17/2026   |   Updated: 3/14/2024   |   Inventor(s): Jaeyun Moon, Kaleab Ayalew, Alexander Barzilov
Keywords(s):  
Category(s): All, Technology Classifications > Therapeutics, Pharmaceuticals, Drug Delivery, Technology Classifications > Medical Devices
A novel device to collect, shape, and concentrate light using reflective conical optics.
Title: A novel device to collect, shape, and concentrate light using reflective conical optics Tech ID: 2022-005 Status: Active Category: Optical Engineering and Photonics Executive Statement: A novel reflective conical device that collects, shapes, and concentrates light with improved efficiency and fidelity compared to traditional lenses. Description: This...
Published: 7/16/2026   |   Updated: 3/14/2024   |   Inventor(s): Michael Pravica
Keywords(s): Engineering & Manufacturing - Sensors & Devices
Category(s): All, Technology Classifications > Therapeutics, Pharmaceuticals, Drug Delivery
A method to create high quality vaccines using tuned monochromatic hard x-rays.
Title: A method to create high quality vaccines using tuned monochromatic hard x-rays. Tech ID: 2023-006 Status: Active Category: Biotechnology & Medical Research Executive Statement: A novel method harnessing tuned monochromatic hard x-rays to produce highly controlled damage to viruses for superior vaccine development and targeted cancer...
Published: 7/15/2026   |   Updated: 3/14/2024   |   Inventor(s): Michael Pravica
Keywords(s): Chemistry, Engineering & Manufacturing, Life Science, Life Science - Biology, Life Science - Health, Sports Performance & Nutrition
Category(s): All, Technology Classifications > Therapeutics, Pharmaceuticals, Drug Delivery
Electrochemistry for vaccine synthesis and tumor destruction
Title: Electrochemistry for Vaccine Synthesis and Tumor Destruction Tech ID: 2023-009 Status: Active Category: Biomedical Electrochemical Technology Executive Statement: A novel electrochemical approach that targets viral genetic material and tumor cells by flowing ionizing current to selectively damage and inactivate harmful biological...
Published: 7/16/2026   |   Updated: 3/14/2024   |   Inventor(s): Michael Pravica
Keywords(s):  
Category(s): All, Technology Classifications > Therapeutics, Pharmaceuticals, Drug Delivery
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