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Smad4 Knockout (Smad4tm1Cxd) Mouse Model for Developmental Biology Studies
Smad4 knockout: Smad4 is essential for epiblast proliferation, egg cylinder formation and mesoderm induction in early embryogenesis. The TGF-beta-related superfamily plays an important role in multiple biological systems including embryogenesis. TGF-beta ligands activate specific receptors, which interact with specific Smad proteins, which in turn...
Published: 4/8/2024
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Inventor(s):
Chuxia Deng
Keywords(s):
DPC4-Null
,
Generation
,
IDXXXX
,
IXXXXX
,
Mice
,
SUPPRESSOR
,
tumor
Category(s):
Collaboration Sought > Licensing
,
Application > Therapeutics
,
Application > Research Materials
,
Application > Diagnostics