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Search Results - stanton+mchardy
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Ammonium compounds for gut microbiome modulation
The technology involves the development of quaternary ammonium compounds with antimicrobial properties, effective against various bacteria and fungi, including multidrug-resistant strains. These compounds concentrate activity in the gastrointestinal tract, minimizing systemic exposure and potential side effects, making them suitable for conditions like...
Published: 9/6/2024
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Inventor(s):
Bryan Davies
,
Stanton McHardy
,
Ashley Cunningham
,
Hua-Yu Wang
Keywords(s):
Category(s):
Life sciences > Therapeutics > Formulation
Novel Capsazepine Analogs to Treat Cancer
Novel compounds have been developed based upon the capsazepine pharmacophore that are effective in halting tumor cell proliferation in vitro and in vivo. Capsazepine is a known, off-patent, analog of Capsaicin that has been proposed and studied as a TRPV1 antagonist for treatment of pain. Although Capsazepine has been proposed for alleviation of pain,...
Published: 5/22/2024
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Inventor(s):
Cara Gonzales
,
Stanton McHardy
Keywords(s):
Category(s):
Clinical Specialty > Oncology
,
Therapeutics > Small Molecule