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Search Results - shira+cramer
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Therapeutic applications of engineered L-Cyst(e)ine-degrading enzymes
The technology describes engineered primate cystathionine-γ-lyase enzymes with specific amino acid modifications that enhance their ability to degrade L-cyst(e)ine. These enzymes, intended for therapeutic use in cancer and cystinuria, improve stability and reduce immunogenicity. Background Cancer and cystinuria present significant therapeutic...
Published: 11/5/2024
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Inventor(s):
George Georgiou
,
Shira Cramer
,
Everett Stone
Keywords(s):
Category(s):
Life sciences > Research tools > Tool/assay/screening platform
,
Life sciences > Therapeutics > Gene therapy